蝙蝠:大自然的活体病毒库
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近期,中东呼吸综合征在韩国暴发,广东省也发现一例输入性病例。这一急性呼吸道疾病由冠状病毒MERS引起,令全球高度关注。而去年在西非肆虐的埃博拉病毒,也让人一度胆战心惊。在这些病毒肆虐的背后,都少不了蝙蝠的身影。研究显示,蝙蝠很可能就是多种病毒的自然宿主,直接感染人类的果子狸、骆驼、灵长类动物等可能只是病毒的中间宿主。
在大多数人心目中,蝙蝠是一种诡异可怕,与死亡和阴暗联系的动物。西方文学影视剧中的吸血鬼形象就是从吸血蝙蝠身上得来的灵感。蝙蝠与病毒确实有着紧密的联系:国际病毒分类委员会鉴定,25个病毒科能够感染脊椎动物,其中10个科与蝙蝠有关;在感染脊椎动物的16个RNA病毒科中,至少有9个科的病毒可感染蝙蝠。可以说,蝙蝠就是一座自然界的活体病毒库。为什么蝙蝠这么“毒”?
1, 蝙蝠带来死亡的阴影
据食性不同,蝙蝠有食虫、食果、食肉、杂食和吸血之分。人类很早就注意到蝙蝠所携带的病毒及其存在的危害。狐蝠科是携带病毒最多的蝙蝠种类,以吃水果为生,又被称为“果蝠”。其他向人类传播病毒的主要蝙蝠种还有犬吻蝠科、叶口蝠科、菊头蝠科和鞘尾蝠科。人们最早注意到的蝙蝠所携带的病毒,是狂犬病毒。到目前为止,对它的研究也最多。2012年最新国际病毒分类委员会报告称,狂犬病毒属有12种,除了蒙哥拉病毒外,其中11种的自然宿主是蝙蝠。
1994年,澳大利亚亨德拉镇的一个赛马场暴发了一场疫情,杀死了14匹赛马和1个人。导致此次疫情的病毒被称为亨德拉病毒,被怀疑来自果蝠。虽然没有发现这种病毒从果蝠直接传播给马,但在实验室的感染研究表明,可能是马取食的牧草被携带病毒的果蝠胎儿组织或胎水污染导致病毒传播。另一种可能的途径是马采食果蝠吃剩的果实而被感染,人与病马接触后“中招”。亨德拉病毒的“近亲”尼帕病毒是世界上最危险的病毒之一,被列为生物安全4级病原。尼帕病最初在1998年到1999年间暴发于马来西亚和新加坡,感染猪群和猪农,276人被感染,其中105人死亡。鉴于与亨德拉的近亲关系,蝙蝠成为第一个怀疑目标。研究证实,果蝠就是尼帕病毒的自然宿主。2004年孟加拉国中部也暴发了尼帕疫情,感染者病死率高达75%,“凶手”也是果蝠。
2003年暴发的SARS疫情让人们记忆犹新。研究结果表明,可能是蝙蝠将体内的SARS病毒在野生动物交易市场传播给果子狸等野生动物。SARS病毒在这些中间宿主体内大量复制并进化后,感染了与其频繁接触的人。去年暴发在西非的埃博拉疫情以其高死亡率和严重症状令人闻之色变。研究发现,果蝠作为埃博拉病毒的自然宿主,通过某种途径,将病毒传染给了灵长类。科学家们推断,可能是灵长类动物在旱季时与果蝠争食水果而被感染。
蝙蝠携带的其他病毒还有我们耳熟能详的禽流感病毒、登革热病毒、流行性乙型脑炎病毒、替曼病毒、罗斯河病毒、基孔肯雅病毒、森林脑炎病毒和汉坦病毒等,其中很多病毒都在近几十年引起过人兽共患病大暴发。越来越多新发致病病毒在蝙蝠体内发现,使得人们逐渐认识到蝙蝠携带病毒的严重性。华南农业大学兽医学院副院长任涛教授介绍,蝙蝠病毒及其携带病毒的机制研究已经成为当前病毒学的研究热点。
2006年前,人们通过各种传统的病毒检测手段,在蝙蝠体内发现了60多种病毒。而一篇发表于2014年的文献指出,通过各种方法人类在蝙蝠体内已经检测到137种病毒,其中61种是人兽共患病毒。尤其是2009年以后,新发现的蝙蝠病毒多达53种,堪比2006年以前发现的病毒种数总和。
是蝙蝠变得更“毒”了吗?任涛认为,其实这些病毒一直存在蝙蝠体内,只是现在把以前没检测到的病毒检出来了。“蝙蝠身上确切携带有多少种病毒,没有人知道,只能发现一种,报道一种。”
我国是世界上蝙蝠分布较广的国家,尤其是西南和东南沿海地区具有热带和亚热带的生态环境,是蝙蝠的重要分布地区。自SARS病毒在我国蝙蝠体内被发现以来,我国高度关注蝙蝠病毒,同时技术的进步也加快了我国蝙蝠病毒检测发现进程。在新发现的53种病毒中,有22种病毒是在中国报道,占41.5%。
2,为何蝙蝠被选为“恶魔使者”?
蝙蝠虽然长相邪恶,但肯定不是因为颜值才被这么多种病毒选中成为它们的使者。研究者认为,蝙蝠成为一系列危险病毒的理想宿主有很多原因。
蝙蝠的生活习性就很有利于病毒的传播。蝙蝠是一种喜欢群居的动物,栖息时会紧紧偎依。墨西哥无尾蝠的栖息地每平米蝙蝠数量达到3000只,一个洞穴总数甚至能达到数百万只。拥挤的环境和亲密的接触使得病毒可以在蝙蝠之间快速传播。
作为唯一能飞的哺乳动物,蝙蝠善于飞行,能随着季节变换进行长途迁徙,这大大增加了病毒的传播范围和几率。在雨林中,蝙蝠的活动范围上至树冠,下至灌木丛,它们所接触到的就不只是取食的水果和昆虫,还有啮齿类动物、猴子、鸟类、蛇类、猩猩和人类。
研究还发现,蝙蝠冬眠时许多生理机能显著下降,免疫系统比平时要迟钝得多,因此对病毒感染不会发生剧烈的免疫反应。而在冬眠的蝙蝠体内,病毒的增殖也变得比较缓慢,低浓度的病毒载量使得蝙蝠并不出现异样症状,但仍可以持续向外排毒。
这种对病毒的耐受不仅仅只是在冬眠期间。日本学者发现,乙型脑炎病毒可以在蝙蝠脑内繁殖,但蝙蝠不会出现任何发病症状。还有科学家研究发现,当蝙蝠被人工感染埃博拉病毒后,病毒可以在蝙蝠体内高度增殖,但蝙蝠本身并不表现出临床症状。
为何蝙蝠携带那么多病毒,自身却安然无恙?他介绍,现在人类对此还没有进行很深入的研究,但蝙蝠可能在血液循环、体温、消化、免疫等方面有特殊的机制。有研究发现,蝙蝠昼夜体温在36℃到39℃之间波动,夜晚体温要比白天高好几度。这可能导致蝙蝠体内的病毒无法稳定增殖。
更重要的是,古老的蝙蝠与病毒在进化中长期“相爱相杀”,已经相互适应和平共处。蝙蝠是最古老的哺乳动物之一,500万年来并没有太多变化,在漫长进化中,蝙蝠与多种多样的病毒相互抗争共同进化,彼此有了很好的适应。
物种的古老使得蝙蝠的病毒更容易传播给别的宿主。介于生命与非生命的病毒在感染一个动物时,往往要与这个动物的细胞受体“对接”才能成功“殖民”。研究发现,蝙蝠体内与病毒“对接”的细胞受体在整个哺乳动物中都最为保守和古老。受体越古老代表这种受体越可能在更多动物体内存在,病毒就更容易从蝙蝠体内传染给其他宿主。
3,谁打开了“潘多拉魔盒”?
种种原因使得蝙蝠成为了一个四处播撒病毒的病毒库,但如果蝙蝠生活远离人类,这些病毒也难以造成威胁。虽然看起来蝙蝠和人类离得比较远,但其实一直就在我们身边。
蝙蝠虽然有翅膀,但其实是一种哺乳动物。“蝙蝠的基因、生活习性等与其他哺乳动物以及人类非常接近,病毒比较容易传染给其他哺乳动物和人类。”任涛说。
蝙蝠的居住地和活动范围多是由其食物决定,而人类的居住地一般都水草丰美,瓜果丰盛,蚊虫也密集,往往会成为蝙蝠的猎食之地。蝙蝠既栖息于自然环境,也可寄居人工环境,包括山洞、岩缝、树林、果园、矿井、坟地、各种人工建筑物。
尽管如此,千百年来蝙蝠与人类并没有闹出多大动静,但是在过去几十年,蝙蝠向人类传播病毒的频率却明显增加。是谁打开了“潘多拉的魔盒”?
任涛表示,这些年来,人类活动范围侵入了蝙蝠的领地,迫使蝙蝠转移栖息地并逐渐融入到人类活动区域内,甚至直接栖息在人类的居住环境。这样毫无疑问地增加了蝙蝠病毒散播的机会。
研究结果表明,马来西亚尼帕病毒疫情的暴发直接与环境破坏有关。森林面积减小、食物不足,迫使狐蝠从传统的森林栖息地中迁移到森林边缘附近的果园取食。而马来西亚有许多养猪场与果园毗邻,狐蝠污染的果实掉落到地上,被猪吃掉,这种致命的病毒就会通过猪传播给人类。
在非洲、东南亚和我国南部一些省份,存在食用蝙蝠的习俗。“很多中国人一直认为蝙蝠是一种药材,可以补这补那。非洲也有一些地区用大网抓蝙蝠来吃。”任涛表示,人类肆无忌惮地捕食野生动物,会把它们的病害带入人类社会。
蝙蝠将病毒传播出去的方式可以归类为5种:蝙蝠直接叮咬或抓伤传播;吸入蝙蝠呼出的带有大量病毒的气溶胶而感染;食肉动物或人捕食带毒蝙蝠造成感染;通过蝙蝠吃过的水果等染毒食物进行传播;蚊子、虱子及蜱等与蝙蝠有关的寄生虫进行传播。
4,人类如何对待蝙蝠?
蝙蝠本来长相就不讨喜,而且还会传播致命的病毒,人类应不应该消灭蝙蝠,免除被病毒感染的后顾之忧?“消灭一个物种是绝对错误的想法,而且人类也没有这个能力。”任涛说,蝙蝠应归类于有益动物,会捕食苍蝇、蚊子等有害昆虫,而且很多珍奇异果的传花授粉都是由蝙蝠完成。
作为全球生物圈中的一分子,蝙蝠在控制昆虫数量、散播植物种子方面有不可忽视的作用,它们的粪便还是自然界丰厚的肥料,蝙蝠的回声定位系统和信号处理方式更是为现代科技中的声纳系统提供了模型。
“虽然蝙蝠是很多疾病的病源,但如果人类不去破坏它的栖息地,多少个世纪以后,它也不容易危害我们。造成感染的后果只能怪人类自己。”任涛说。
其实,目前人类对于蝙蝠与病毒之间的关系仍然知之甚少,病毒在蝙蝠体内增殖、免疫与抗感染等情况也基本不了解,加强对这方面的研究对蝙蝠病毒的防控以及对人类和其他动物疾病的研究将有重要的借鉴意义。
但研究蝙蝠也存在着很多困难。任涛表示,全世界有1000多种蝙蝠,可能已有将近半数的蝙蝠因人类的生态破坏而灭亡,而许多也都处于濒危状态。蝙蝠是一种非常聪明的动物,它可以回声定位、知道躲避,抓捕很困难,在实验室中人工养殖并研究其习性也很不容易。同时,蝙蝠属于夜间飞行动物,这也加大了科学家的研究难度。(本文来源:南方日报 )
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