2,Development of Vaccines: From Discovery to Clinical Testing(2011):wwwkkk83 友情提供 Leading experts guide you step by step to a successful clinical vaccine trial Development of Vaccines sets forth the issues and the challenges of vaccine development and the solutions needed to seamlessly advance a biologic drug formulation from discovery through all the essential steps that lead to a successful clinical vaccine trial. The authors skillfully guide you through everything you need to know, including current analytical tools and techniques, vaccine expression, purification, formulation, and preclinical testing. Not only does the book guide you through lab work, it also explains the regulatory submissions process, helping you gather and report the necessary data.
Divided into five sections, this book serves as a reference to all the critical steps that take place from discovery to clinical trials:
1 Details all the tools needed for immunogen design and development
2 Investigates vaccine platforms, including virus-like particles, nanocapsules, DNA vaccines, and protein expression and purification
3 Explains the spectroscopy and biophysics techniques needed for accurate immunogen characterization
4 Demonstrates how to optimize formulations and evaluate stability
5 Details all the steps needed to file a new application for clinical vaccine testing
Each chapter of the book has been authored by one or more leading authorities with expertise spanning the critical areas of vaccine expression, purification, formulation, preclinical testing, and regulatory submission. Their contributions are not only based on a thorough review of the literature, but also their own hands-on lab bench experience, making this an unsurpassed guide to all stages of vaccine development. http://s.dbank.com/e0atun8gm3/访问密码:DOVvaccine 或者:http://1000eb.com/66mq 或:http://good.gd/1875623.htm
3,Vaccines, 5th Edition (Stanley A. Plotkin) Crazy 友情提供
Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues.Offers comprehensive coverage of both existing vaccines and vaccines currently in the research and development stage.
Examines vaccine stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease control strategies.Analyses the cost-benefit and cost-effectiveness of vaccines. Discusses the proper use of immune globulins and antitoxins. Illustrates concepts and objective data with approximately 600 tables and figures. Website Features Consult the book from any computer at home, in your office, or at any practice location.
Instantly locate the answers to your clinical questions via a simple search query. Quickly find out more about any bibliographical citation by linking to its MEDLINE abstract.
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4,Vaccine Protocols (Methods in Molecular Medicine),2e,2003 silongs 友情提供
This extensively revised, updated, and expanded second edition of a classic laboratory manual applies new understanding of molecular mechanisms to the rational design and development of vaccines. Here the working researcher will find readily reproducible techniques for the development and production of live attenuated vaccines, and vaccines based on inactivated toxins, peptides, and polysaccharide conjugates. New to this edition are cutting-edge chapters on two different viral vectors (Vaccinia and Semliki Forest), lactic acid bacteria for delivery of foreign antigens, incorporation of immunomodulators into plasmid DNA vaccines, construction of tetramer complexes to detect CMI responses, assessment of functional antibody responses, and the use of complete genome sequences for vaccine design. There are also chapters describing more general techniques for vaccine formulation, delivery, and assessment of immune responses, and review discussions of scale-up to manufacture, vaccine quality assurance, and clinical trials
下载链接: http://rapidshare.com/files/61592395/087-Vaccine_Protocols_2nd_Edition.pdf
6,经典的流感病毒和疫苗培训幻灯 (凯荣出品)mrwlz 友情提供 http://biosky.haotui.com/viewthread.php?tid=30905&extra=page%3D1%26amp%3Bfilter%3Dtype%26amp%3Btypeid%3D102
7,09年疫苗新书:Vaccines for Biodefense and Emerging and Neglected Diseases wwwkkk83 友情提供
The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs them of what they need to do if they are currently working on developing a vaccine. http://rapidshare.com/files/4062 ... 1stEdition.zip.html
8,Strategic trends in the vaccine market中英文对照初稿 dudupan 友情提供 请见附件