Brian J. McMahon，CDC，阿拉斯加——HBV相关实验室及人物介绍系列

Brian J. McMahon，CDC，阿拉斯加
National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention

Brown, R. J. and B. J. McMahon, et al. (2016). "Antiviral therapy in chronic hepatitis B viral infection during pregnancy: A systematic review and meta-analysis." Hepatology 63(1): 319-33.
Gounder, P. P. and L. R. Bulkow, et al. (2016). "Nested case-control study: hepatocellular carcinoma risk after hepatitis B surface antigen seroclearance." Aliment Pharmacol Ther 43(11): 1197-207.
Simons, B. C. and P. R. Spradling, et al. (2016). "A longitudinal hepatitis B vaccine cohort demonstrates long-lasting hepatitis B cellular immunity despite loss of antibody against hepatitis B surface antigen." J Infect Dis.
Livingston, S. E. and L. J. Townshend-Bulson, et al. (2016). "Results of interferon-based treatments in Alaska Native and American Indian population with chronic hepatitis C." Int J Circumpolar Health 75: 30696.
Ching, L. K. and P. P. Gounder, et al. (2016). "Incidence of Hepatocellular Carcinoma According to Hepatitis B Virus Genotype in  Alaska Native People." Liver Int.
Bruce, M. G. and D. Bruden, et al. (2016). "Antibody Levels and Protection After Hepatitis B Vaccine: Results of a 30-Year Follow-up Study and Response to a Booster Dose." J Infect Dis.
Spradling, P. R. and L. R. Bulkow, et al. (2016). "Persistence of seropositivity among persons vaccinated for hepatitis A during infancy by maternal antibody status: 15-year follow-up." Hepatology 63(3): 703-11.
McMahon, B. J. (2016). "Combination of Pegylated Interferon and Tenofovir for Hepatitis B Treatment: Screening and Counseling of Patients are Warranted." Gastroenterology 150(1): 32-4.
Lok, A. S. and B. J. McMahon, et al. (2016). "Antiviral therapy for chronic hepatitis B viral infection in adults: A systematic review and meta-analysis." Hepatology 63(1): 284-306.
Jonas, M. M. and A. S. Lok, et al. (2016). "Antiviral therapy in management of chronic hepatitis B viral infection in children: A systematic review and meta-analysis." Hepatology 63(1): 307-18.
McMahon, B. J. (2015). "Two Key Components to Address Chronic Hepatitis B in Children: Detection and Prevention." J Pediatr 167(6): 1186-7.
Liang, T. J. and T. M. Block, et al. (2015). "Present and future therapies of hepatitis B: From discovery to cure." Hepatology 62(6): 1893-908.
Spradling, P. R. and L. Bulkow, et al. (2014). "Prevalence and causes of elevated serum aminotransferase levels in a population-based cohort of persons with chronic hepatitis B virus infection." J Hepatol 61(4): 785-91.
Keck, J. W. and L. R. Bulkow, et al. (2014). "Hepatitis B virus antibody levels 7 to 9 years after booster vaccination in Alaska native persons." Clin Vaccine Immunol 21(9): 1339-42.
Ferucci, E. D. and T. L. Choromanski, et al. (2014). "Autoimmune hepatitis in the Alaska Native population: autoantibody profile and HLA associations." Liver Int 34(8): 1241-9.
Beckett, G. A. and J. M. Block, et al. (2014). "The role of primary care physician assistants in managing chronic hepatitis B." JAAPA 27(3): 51-4.
McMahon, B. J. (2014). "Chronic hepatitis B virus infection." Med Clin North Am 98(1): 39-54.
McMahon, B. J. and L. Bulkow, et al. (2014). "Relationship between level of hepatitis B virus DNA and liver disease: a population-based study of hepatitis B e antigen-negative persons with hepatitis B." Clin Gastroenterol Hepatol 12(4): 701-6.e1-3.
Tohme, R. A. and L. Bulkow, et al. (2013). "Rates and risk factors for hepatitis B reactivation in a cohort of persons in the inactive phase of chronic hepatitis B-Alaska, 2001-2010." J Clin Virol 58(2): 396-400.
McMahon, B. J. (2013). "Hepatocellular carcinoma and hepatitis B virus: family matters." Clin Gastroenterol Hepatol 11(12): 1646-7.
Spradling, P. R. and B. Simons, et al. (2013). "Incidence of diabetes mellitus in a population-based cohort of persons with chronic hepatitis B virus infection." J Viral Hepat 20(7): 510-3.
Kowalec, K. and G. Y. Minuk, et al. (2013). "Genetic diversity of hepatitis B virus genotypes B6, D and F among circumpolar indigenous individuals." J Viral Hepat 20(2): 122-30.
Sharapov, U. M. and L. R. Bulkow, et al. (2012). "Persistence of hepatitis A vaccine induced seropositivity in infants and young children by maternal antibody status: 10-year follow-up." Hepatology 56(2): 516-22.
McMahon, B. J. and B. C. Simons (2012). "Interpreting hepatitis B surface antigen levels: useful clinical test or just another confusing assay?" Clin Gastroenterol Hepatol 10(3): 218-9.
McMahon, B. J. and J. Block, et al. (2012). "Internist diagnosis and management of chronic hepatitis B virus infection." Am J Med 125(11): 1063-7.
Lok, A. S. and J. W. Ward, et al. (2012). "Reactivation of hepatitis B during immunosuppressive therapy: potentially fatal yet preventable." Ann Intern Med 156(10): 743-5.
McHugh, J. A. and S. Cullison, et al. (2011). "Chronic hepatitis B infection: a workshop consensus statement and algorithm." J Fam Pract 60(9): E1-8.
McMahon, B. J. and L. R. Bulkow, et al. (2011). "Elimination of hepatocellular carcinoma and acute hepatitis B in children 25 years after a hepatitis B newborn and catch-up immunization program." Hepatology 54(3): 801-7.
Ferucci, E. D. and K. J. Hurlburt, et al. (2011). "Azathioprine metabolite measurements are not useful in following treatment of autoimmune hepatitis in Alaska Native and other non-Caucasian people." Can J Gastroenterol 25(1): 21-7.
Cohen, C. and S. D. Holmberg, et al. (2011). "Is chronic hepatitis B being undertreated in the United States?" J Viral Hepat 18(6): 377-83.
Singleton, R. J. and S. Hess, et al. (2010). "Impact of a statewide childhood vaccine program in controlling hepatitis A virus  infections in Alaska." Vaccine 28(38): 6298-304.
McMahon, B. J. (2010). "Hepatitis B surface antigen (HBsAg): a 40-year-old hepatitis B virus seromarker gets new life." Gastroenterology 139(2): 380-2.
Simonetti, J. and L. Bulkow, et al. (2010). "Clearance of hepatitis B surface antigen and risk of hepatocellular carcinoma in  a cohort chronically infected with hepatitis B virus." Hepatology 51(5): 1531-7.
McMahon, B. J. and D. Bruden, et al. (2010). "Adverse outcomes in Alaska natives who recovered from or have chronic hepatitis C infection." Gastroenterology 138(3): 922-31.e1.
Borresen, M. L. and O. R. Olsen, et al. (2010). "Hepatitis D outbreak among children in a hepatitis B hyper-endemic settlement in  Greenland." J Viral Hepat 17(3): 162-70.
McMahon, B. J. (2010). "Recent advances in managing hepatitis B." F1000 Med Rep 2.
Jonas, M. M. and J. M. Block, et al. (2010). "Treatment of children with chronic hepatitis B virus infection in the United States: patient selection and therapeutic options." Hepatology 52(6): 2192-205.
Livingston, S. E. and H. Deubner, et al. (2010). "Factors associated with the progression of fibrosis on liver biopsy in Alaska Native and American Indian persons with chronic hepatitis C." Can J Gastroenterol 24(7): 445-51.
McMahon, B. J. (2010). "Natural history of chronic hepatitis B." Clin Liver Dis 14(3): 381-96.
Haber, B. A. and J. M. Block, et al. (2009). "Recommendations for screening, monitoring, and referral of pediatric chronic hepatitis B." Pediatrics 124(5): e1007-13.
McMahon, B. J. and C. M. Dentinger, et al. (2009). "Antibody levels and protection after hepatitis B vaccine: results of a 22-year follow-up study and response to a booster dose." J Infect Dis 200(9): 1390-6.
Lok, A. S. and B. J. McMahon (2009). "Chronic hepatitis B: update 2009." Hepatology 50(3): 661-2.
McMahon, B. J. (2009). "The influence of hepatitis B virus genotype and subgenotype on the natural history of chronic hepatitis B." Hepatol Int 3(2): 334-42.
Golden-Mason, L. and B. E. Palmer, et al. (2009). "Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus  infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells." J Virol 83(18): 9122-30.
McMahon, B. J. (2009). "The natural history of chronic hepatitis B virus infection." Hepatology 49(5 Suppl): S45-55.
McMahon, B. J. (2008). "Implementing evidenced-based practice guidelines for the management of chronic hepatitis B virus infection." Am J Med 121(12 Suppl): S45-52.
Hammitt, L. L. and L. Bulkow, et al. (2008). "Persistence of antibody to hepatitis A virus 10 years after vaccination among children and adults." J Infect Dis 198(12): 1776-82.
McMahon, B. J. (2008). "Natural history of chronic hepatitis B - clinical implications." Medscape J Med 10(4): 91.
Li, H. and L. V. Thomassen, et al. (2008). "Investigation of putative multisubtype hepatitis C virus infections in vivo by heteroduplex mobility analysis of core/envelope subgenomes." J Virol 82(15): 7524-32.
Li, H. and B. J. McMahon, et al. (2008). "Hepatitis C virus envelope glycoprotein co-evolutionary dynamics during chronic hepatitis C." Virology 375(2): 580-91.
Bruce, M. G. and D. Bruden, et al. (2008). "Clinical significance of elevated alpha-fetoprotein in Alaskan Native patients with chronic hepatitis C." J Viral Hepat 15(3): 179-87.
Bell, B. P. and S. Negus, et al. (2007). "Immunogenicity of an inactivated hepatitis A vaccine in infants and young children." Pediatr Infect Dis J 26(2): 116-22.
Lok, A. S. and B. J. McMahon (2007). "Chronic hepatitis B." Hepatology 45(2): 507-39.
Livingston, S. E. and J. P. Simonetti, et al. (2007). "Hepatitis B virus genotypes in Alaska Native people with hepatocellular carcinoma: preponderance of genotype F." J Infect Dis 195(1): 5-11.
Sakamoto, T. and Y. Tanaka, et al. (2007). "Classification of hepatitis B virus genotype B into 2 major types based on characterization of a novel subgenotype in Arctic indigenous populations." J Infect Dis 196(10): 1487-92.
Tulisov, A. and B. J. McMahon, et al. (2007). "Viral hepatitis in the Arctic. A review from a Circumpolar Workshop on Viral hepatitis, ICCH13." Alaska Med 49(2 Suppl): 193-203.
Livingston, S. E. and J. P. Simonetti, et al. (2007). "Clearance of hepatitis B e antigen in patients with chronic hepatitis B and genotypes A, B, C, D, and F." Gastroenterology 133(5): 1452-7.
Hammitt, L. L. and T. W. Hennessy, et al. (2007). "Hepatitis B immunity in children vaccinated with recombinant hepatitis B vaccine  beginning at birth: a follow-up study at 15 years." Vaccine 25(39-40): 6958-64.
Samandari, T. and A. E. Fiore, et al. (2007). "Differences in response to a hepatitis B vaccine booster dose among Alaskan children and adolescents vaccinated during infancy." Pediatrics 120(2): e373-81.
Hurlburt, K. J. and B. J. McMahon, et al. (2007). "Hepatitis B-associated vasculitis in Alaska Natives: viral genotype, clinical and serologic outcome." Liver Int 27(5): 627-32.
McMahon, B. J. (2006). "Selecting appropriate management strategies for chronic hepatitis B: who to treat." Am J Gastroenterol 101 Suppl 1: S7-12.
Dentinger, C. M. and B. J. McMahon, et al. (2005). "Persistence of antibody to hepatitis B and protection from disease among Alaska natives immunized at birth." Pediatr Infect Dis J 24(9): 786-92.
McMahon, B. J. (2005). "Epidemiology and natural history of hepatitis B." Semin Liver Dis 25 Suppl 1: 3-8.
McMahon, B. J. and D. L. Bruden, et al. (2005). "Antibody levels and protection after hepatitis B vaccination: results of a 15-year follow-up." Ann Intern Med 142(5): 333-41.
McMahon, B. J. (2004). "Viral hepatitis in the Arctic." Int J Circumpolar Health 63 Suppl 2: 41-8.
Petersen, K. M. and L. R. Bulkow, et al. (2004). "Duration of hepatitis B immunity in low risk children receiving hepatitis B vaccinations from birth." Pediatr Infect Dis J 23(7): 650-5.
Lok, A. S. and B. J. McMahon (2004). "[AASLD Practice Guidelines. Chronic hepatitis B: update of therapeutic guidelines]." Rom J Gastroenterol 13(2): 150-4.
McMahon, B. J. (2004). "The natural history of chronic hepatitis B virus infection." Semin Liver Dis 24 Suppl 1: 17-21.
Lok, A. S. and B. J. McMahon (2004). "Chronic hepatitis B: update of recommendations." Hepatology 39(3): 857-61.
Williams, J. L. and D. A. Bruden, et al. (2003). "Hepatitis A vaccine: immunogenicity following administration of a delayed immunization schedule in infants, children and adults." Vaccine 21(23): 3208-11.
Ferber, M. J. and D. P. Montoya, et al. (2003). "Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers." Oncogene 22(24): 3813-20.
Peach, D. and B. J. McMahon, et al. (2002). "Impact of recurrent epidemics of hepatitis a virus infection on population immunity levels: Bristol Bay, Alaska." J Infect Dis 186(8): 1081-5.
Lok, A. S. and B. J. McMahon (2001). "Chronic hepatitis B." Hepatology 34(6): 1225-41.
McMahon, B. J. and P. Holck, et al. (2001). "Serologic and clinical outcomes of 1536 Alaska Natives chronically infected with  hepatitis B virus." Ann Intern Med 135(9): 759-68.
Williams, J. L. and C. J. Christensen, et al. (2001). "Evaluation of the response to a booster dose of hepatitis B vaccine in previously immunized healthcare workers." Vaccine 19(28-29): 4081-5.
McMahon, B. J. and L. Bulkow, et al. (2000). "Screening for hepatocellular carcinoma in Alaska natives infected with chronic hepatitis B: a 16-year population-based study." Hepatology 32(4 Pt 1): 842-6.
Gandhi, M. J. and G. G. Yang, et al. (2000). "Hepatitis B virions isolated with antibodies to the pre-S1 domain reveal occult viremia by PCR in Alaska Native HBV carriers who have seroconverted." Transfusion 40(8): 910-6.
Harpaz, R. and B. J. McMahon, et al. (2000). "Elimination of new chronic hepatitis B virus infections: results of the Alaska immunization program." J Infect Dis 181(2): 413-8.
Chung, Y. H. and A. M. Di Bisceglie, et al. (1999). "Hepatocellular carcinoma not related to hepatitis B virus infection among Alaska  natives." Int J Circumpolar Health 58(3): 208-13.
McMahon, B. J. (1998). "Chronic carriers of hepatitis B virus who clear hepatitis B surface antigen: are  they really "off the hook"?" Hepatology 28(1): 265-7.
McMahon, B. J. and A. P. Lanier, et al. (1998). "Hepatitis B and hepatocellular carcinoma in Eskimo/Inuit population." Int J Circumpolar Health 57 Suppl 1: 414-9.
Bulkow, L. R. and R. B. Wainwright, et al. (1998). "Increases in levels of antibody to hepatitis B surface antigen in an immunized population." Clin Infect Dis 26(4): 933-7.
Silva, A. E. and B. J. McMahon, et al. (1998). "Hepatitis B virus DNA in persons with isolated antibody to hepatitis B core antigen who subsequently received hepatitis B vaccine." Clin Infect Dis 26(4): 895-7.
Keeffe, E. B. and S. Iwarson, et al. (1998). "Safety and immunogenicity of hepatitis A vaccine in patients with chronic liver disease." Hepatology 27(3): 881-6.
Wainwright, R. B. and L. R. Bulkow, et al. (1997). "Protection provided by hepatitis B vaccine in a Yupik Eskimo population--results  of a 10-year study." J Infect Dis 175(3): 674-7.
Parkinson, A. J. and B. J. McMahon, et al. (1996). "Detection of alpha-fetoprotein and hepatitis-B surface antigen in blood spotted on filter paper: use as a screen for hepatocellular carcinoma in Alaska Natives." Arctic Med Res 55(3): 123-8.
Liang, T. J. and K. Hasegawa, et al. (1994). "Hepatitis B virus precore mutation and fulminant hepatitis in the United States.  A polymerase chain reaction-based assay for the detection of specific mutation." J Clin Invest 93(2): 550-5.
Bulkow, L. R. and B. J. McMahon, et al. (1993). "Safety and immunogenicity of a combined hepatitis B virus-Haemophilus influenzae  type B vaccine formulation in healthy adults." Arctic Med Res 52(3): 118-26.
McMahon, B. J. and S. Schoenberg, et al. (1993). "Seroprevalence of hepatitis B viral markers in 52,000 Alaska Natives." Am J Epidemiol 138(7): 544-9.
McMahon, B. J. and A. J. Parkinson, et al. (1992). "Response to hepatitis B vaccine of persons positive for antibody to hepatitis B core antigen." Gastroenterology 103(2): 590-4.
McMahon, B. J. and C. Helminiak, et al. (1992). "Frequency of adverse reactions to hepatitis B vaccine in 43,618 persons." Am J Med 92(3): 254-6.
McMahon, B. J. (1991). "Prevention of viral hepatitis in circumpolar populations." Arctic Med Res 50(4): 187-90.
Wainwright, R. B. and B. J. McMahon, et al. (1991). "Protection provided by hepatitis B vaccine in a Yupik Eskimo population. Seven-year results." Arch Intern Med 151(8): 1634-6.
McMahon, B. J. and S. R. Alberts, et al. (1990). "Hepatitis B-related sequelae. Prospective study in 1400 hepatitis B surface antigen-positive Alaska native carriers." Arch Intern Med 150(5): 1051-4.
McMahon, B. J. and K. Wainwright, et al. (1990). "Response to hepatitis B vaccine in Alaska natives with chronic alcoholism compared with non-alcoholic control subjects." Am J Med 88(5): 460-4.
Parkinson, A. J. and B. J. McMahon, et al. (1990). "Comparison of enzyme immunoassay with radioimmunoassay for the detection of antibody to hepatitis B core antigen as the only marker of hepatitis B infection  in a population with a high prevalence of hepatitis B." J Med Virol 30(4): 253-7.
McMahon, B. J. (1989). "Immunization of newborns of HBsAg-positive mothers: a successful first step in control of hepatitis B virus in Taiwan." Hepatology 9(6): 900-2.
Wainwright, R. B. and B. J. McMahon, et al. (1989). "Duration of immunogenicity and efficacy of hepatitis B vaccine in a Yupik Eskimo  population." JAMA 261(16): 2362-6.
McMahon, B. J. and W. L. Heyward, et al. (1989). "Hepatitis B-associated polyarteritis nodosa in Alaskan Eskimos: clinical and epidemiologic features and long-term follow-up." Hepatology 9(1): 97-101.
Popper, H. and S. N. Thung, et al. (1988). "Evolution of hepatocellular carcinoma associated with chronic hepatitis B virus infection in Alaskan Eskimos." Arch Pathol Lab Med 112(5): 498-504.
McMahon, B. J. (1988). "Workshop on hepatitis B in circumpolar countries. Summary of the hepatitis B workshop." Arctic Med Res 47 Suppl 1: 705-7.
McGlynn, K. A. and E. D. Lustbader, et al. (1987). "Hepatitis B virus replication and tuberculin reactivity: studies in Alaska." Am J Epidemiol 126(1): 38-43.
McMahon, B. J. and E. R. Rhoades, et al. (1987). "A comprehensive programme to reduce the incidence of hepatitis B virus infection  and its sequelae in Alaskan natives." Lancet 2(8568): 1134-6.
Wainwright, R. B. and B. J. McMahon, et al. (1986). "Prevalence of hepatitis B virus infection in Tonga: identifying high risk groups  for immunization with hepatitis B vaccine." Int J Epidemiol 15(4): 567-71.
Welch, H. G. and B. Lazar, et al. (1986). "Nifedipine--induced hepatitis." Alaska Med 28(1): 11-2.
Heyward, W. L. and A. P. Lanier, et al. (1985). "Early detection of primary hepatocellular carcinoma. Screening for primary hepatocellular carcinoma among persons infected with hepatitis B virus." JAMA 254(21): 3052-4.
Heyward, W. L. and T. R. Bender, et al. (1985). "The control of hepatitis B virus infection with vaccine in Yupik Eskimos. Demonstration of safety, immunogenicity, and efficacy under field conditions." Am J Epidemiol 121(6): 914-23.
McMahon, B. J. and W. L. Alward, et al. (1985). "Acute hepatitis B virus infection: relation of age to the clinical expression of  disease and subsequent development of the carrier state." J Infect Dis 151(4): 599-603.
Alward, W. L. and B. J. McMahon, et al. (1985). "The long-term serological course of asymptomatic hepatitis B virus carriers and the development of primary hepatocellular carcinoma." J Infect Dis 151(4): 604-9.
Schreeder, M. T. and T. R. Bender, et al. (1983). "Prevalence of hepatitis B in selected Alaskan Eskimo villages." Am J Epidemiol 118(4): 543-9.
Heyward, W. L. and T. R. Bender, et al. (1982). "Serological markers of hepatitis B virus and alpha-fetoprotein levels preceding primary hepatocellular carcinoma in Alaskan Eskimos." Lancet 2(8304): 889-91.
McMahon, B. J. and T. R. Bender, et al. (1981). "Delayed development of antibody to hepatitis B surface antigen after symptomatic  infection with hepatitis B virus." J Clin Microbiol 14(2): 130-4.
McMahon, B. J. and W. L. Heyward, et al. (1980). "A prospective study of hepatitis B virus serologic markers and liver enzymes." J Infect Dis 142(5): 772.
McMahon, B. J. and T. R. Bender, et al. (1980). "Vasculitis in Eskimos living in an area hyperendemic for hepatitis B." JAMA 244(19): 2180-2.
Anuras, S. and B. J. McMahon, et al. (1980). "Severe abdominal vasculitis with hepatitis B antigenemia." Am J Surg 140(5): 692-5.