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& Q3 M4 N3 e( }, L! EViral Pathogenesis and Immunity 2nd 名著再版: n2 k( \1 l- I) {! O% U
【书名版次】：Viral Pathogenesis and Immunity Second（Second edition）
5 Z( B" D7 k: @4 A+ {( E& U【作 者】：Neal Nathanson
0 r* _3 ~5 V% M2 x- L$ X0 d3 J9 w8 r【出 版 社】: Academic Press' J k8 L/ X) \% @
【简 介】：7 T, H9 M2 _/ _ u! `! W
名著再版 " B0 L# j6 c# t: f) c
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This book is the direct offspring of Viral Pathogenesis,
! h! }, f) P& e' E' y* Epublished in 1997. Having read several drafts of all the
& d# ? o2 J! f. _6 T6 {chapters in Viral Pathogenesis, it was clear that the large) e% f- u! S% ]
book contained a wealth of information, but that it was
* U/ `* ~; x- \: Y K6 N2 b% ?unsuited for readers who desired an introduction to the
1 l& Y: z7 ^& l4 y* o$ x6 ktopic. From that observation sprang the plan for a short
1 L4 T: z- h: K* ]' j2 Rversion that could be used as an introductory text or for
4 Y# b1 [% }( [8 L( Yself-education.. @/ {' n3 B. c! @
An introductory text clearly benefits from the
/ t: o% D6 i6 E8 r$ ?/ `coherence provided by a single author, but suffers from9 A1 N- j& V# x2 ^" d, }- v
the finite expertise of any single researcher. Therefore, a I/ x* \" E9 M# n( U
compromise was devised, in which each chapter was coauthored
5 ~( K4 t: Q8 Mby an expert in the specific area under consideration.. V3 a; T6 e% J$ ?$ _
This strategy was facilitated by the successful g3 r! [9 P7 t. W8 T
collaborations that had been developed during the* e; a# J7 C5 F1 Y6 U7 i5 A. v* J
preparation of Viral Pathogenesis. The text includes
+ v9 R3 K# N9 Q4 L. \9 ?references published through to June, 2006.
: D# b# g( w6 P1 n; F; uI would like to acknowledge the contributions of the
3 b$ y5 P4 H ?, u" a* X3 `co-authors. Their advice and expertise has been essential
( F" U# `, s hto the planning and execution of this undertaking and it3 T( B7 ^% ]* U( C$ Y7 E% z& |
has been a continual pleasure to work with them. They. f( w# V2 x6 g' ]# O
have provided extremely cogent suggestions that have
\8 I R5 Y6 agiven the book an enhanced level of authority that could8 z$ n& P" K0 a) |
not otherwise have been achieved.- d* \. b% L D1 \8 `4 e
Lisa Tickner and the staff at Academic Press,% i5 X" ?1 H2 b! w( Q3 |
London, have been an ongoing source of support both
$ N* c6 t# B! {# X* R4 A# \+ Fbecause of their enthusiasm for this book and their U @6 P7 |2 b0 s b
highly professional expertise in all phases of the project.9 E6 H a- e# B. E4 K$ Y- J
Wendy Jackelow provided the outstanding illustrations, s( u$ R d+ p4 N3 F2 P
rendered from a wide variety of often primitive sketches.
- U0 D3 ]; a$ `# ?1 W; VNeal Nathanson/ V- S! X9 l1 ~% z0 v7 q
Philadelphia
3 e# [$ X' g# @( f% |+ I【出版日期】：2007
1 m2 c7 W3 L* F3 X【Contents】: |7 l. ~% f3 |2 {2 c* u, I; z
8 Y( w& C# ^) M# a/ KList of Co-authors vii! M7 X; T4 \' x: G" W; ]
Preface ix& ]. }: \; X( g. U
Introduction xi
+ M& Q4 L! z. OPart I Essentials of Viral Pathogenesis 1
$ P% w- f, ^- x' {1 Historical Roots 3
+ U! E. m* r7 f& c- r! a, B+ D; eNeal Nathanson and Frederick A.Murphy7 @& z' A$ f, h" }' Q z* M
2 The Sequential Steps in Viral Infection 14
- W. p5 w$ ^+ I$ VNeal Nathanson and Frederick A.Murphy
e7 C6 W. H( h1 c; _9 u3 Cellular Receptors and Viral Tropism 277 k7 B; s2 V0 }9 L2 M' l; X
Neal Nathanson and Kathryn V. Holmes
; S: G; X0 W9 W. o3 c1 p0 T4 Virus–Cell Interactions 41
- G& B9 A( m& u, I, M# h; S" d" lNeal Nathanson and Diane E. Griffin
( Q! L# Q+ P( \5 W) e# ~5 HPart II Host Responses to Viral Infection 57
A8 {0 T0 k p5 Innate Immunity 59
- i% Y* e2 L- `0 o: a3 ^Neal Nathanson and Christine A. Biron
. m) M n; Q4 X5 a3 g: F6 Immune Responses to Viral Infection 72
/ {% \- z# R! b2 I% R! D( uNeal Nathanson and Rafi Ahmed+ Y9 E4 @9 G' ?& z. F1 l" F
7 Virus-Induced Immunopathology 88
3 V# d( y; V2 k! |9 c0 lNeal Nathanson and Rafi Ahmed% O0 G) x3 F4 x: N2 ?
8 Virus-Induced Immunosuppression 99- g, K+ P+ c7 c) s- J
Neal Nathanson and Diane E. Griffin$ l o) x3 G& G9 a4 s: D" ^, a
Part III Virus–Host Interactions 111
/ q& V+ X h) U' b9 Viral Virulence 113
$ n7 n9 @! I' u: @. R( M$ XNeal Nathanson and Francisco
4 \* E1 P$ {$ R4 H2 w# H" b8 GGonzalez-Scarano4 Y; P7 T& k' F: J$ f
10 Viral Persistence 130
5 a7 D3 d4 U8 o/ k `. GNeal Nathanson and Francisco- i3 E2 l! {. R8 W9 }( m
Gonzalez-Scarano
5 y* |$ {( h+ v% @. S11 Viral Oncogenesis: Retroviruses 146
& l* D% O* d' l, U3 A& b; `) V3 UNeal Nathanson and Harriet L. Robinson( c# w% B F4 M L3 W7 Q
12 Viral Oncogenesis: DNA Viruses 158
( R8 o& y. F: X) E. }Neal Nathanson and Erle S. Robertson
/ y6 G' A4 h5 d3 R# A13 Host Susceptibility to Viral Diseases 1747 t) N4 U4 u C
Neal Nathanson and Margo A. Brinton
- T0 p3 b" ^2 A0 h# g5 e3 ]14 HIV, SIV and the Pathogenesis of AIDS 185
1 h4 s) f9 M# k0 c }Neal Nathanson and Julie Overbaugh2 r- T* D5 I2 K3 v Q
Part IV Ecology and Control of Viral 201
* n+ O, m9 U0 A8 O. Y1 ~ g; s& kInfections3 [& K5 z" L$ }0 O, N0 d0 A
15 Emerging Viral Diseases 2038 Y& z- s# |7 }
Neal Nathanson and Frederick A.Murphy" v$ z" i2 k( r9 F0 e9 n
16 Antiviral Therapy 221' l/ F2 E& i g) U$ X3 N
Neal Nathanson and Douglas D. Richman
2 c/ |! ~; [) ?9 O17 Viral Vaccines 2347 @5 |5 b4 S! u O& ~
Neal Nathanson and Harriet L. Robinson
( I r, i# [. ^: u: \" t+ N% jGlossary and Abbreviations 253
4 S( g& O5 W) U* K# o9 W5 eIndex 259
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