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地板
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发表于 2015-9-5 15:42:07
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casarett 发表于 2013-7-9 11:35:
用特殊病毒尤其是用乙肝病毒、而非用传统模式病毒如LCMV,能够解析出具有共性或较为普遍的免疫学和病毒学问题,这是难能可贵的,尤其是在中国。希望DR LI能够在肝炎病毒尤其在乙肝病毒抗病毒免疫、免疫耐受、甚至一些重要的纯免疫学问题上有更多具有意义的建树。
同样,我们也应该学习DR LI是如何提出一个好的科学问题的。
另外,不才一直认为用乙肝病毒作为“模式病毒”探讨现在免疫学上的很多或者说一些重要问题,如免疫耐受的维持和打破,具有其他模式病毒所没有的优势。至少我相信在肝脏免疫学的研究中用HBV作为模式病毒比较有优势!
再次祝贺Dr. Li !!!!!!!!!!!!!
It’s well known that many important immune and virological problems have been addressed via using regular model viruses, such as LCMV. Therefore, It is extremely hard, or rare to address critically important immunological issues using hepatitis B virus, but Dr. Li et al. have successfully achieved this goal. Excellently Done! This is not easy but very hard, especially in China. Hope Dr. Li will succeed in anti-viral immunity, and immune tolerance against HBV, or in some importantly pure immunologic issues in his future professional development.
Obviously, there are some valuable experiences for our reference from Dr. Li’s present excellent story. Maybe most important is how to find a good or important scientific problem for tackling.
Personally speaking, HBV has some unique advantages over other common model viruses for resolving some immune issues, such as maintenance or breaking of immune tolerance. I believe HBV is a good model virus for hepatic immunity research at least!
Congratulations again, Dr. Li!!!!!!!!
Attached: article+supplementary materials:
http://www.fileswap.com/dl/DrD88twuqf/ |
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