[转移帖]英调查称儿童期疫苗与自闭症相关研究属骗局

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原帖由论坛会员503814发表于 2011-1-6 22:04 :

据美国《纽约时报》1月5日报道，英国一项最新调查揭露，将儿童期疫苗与自闭症相关联的首项研究纯属骗人的把戏，因为其中涉及的参试儿童数据为篡改信息。

1998年安德鲁·韦克菲尔德及其同事在英国《柳叶刀》杂志上发表研究报告指出，麻疹腮腺炎风疹三联疫苗(MMR)和自闭症及肠道疾病有关。该研究导致全球父母受到惊吓，麻疹、腮腺炎和风疹三联疫苗接种率一直处于低谷。

最新调查将韦克菲尔德报告中的诊断数据与医院病历进行了对比研究，结果发现，韦克菲尔德及其同事擅自篡改了参试患者的病历。

英国《太阳报》记者布莱恩·迪尔发表的最新调查报告指出，尽管韦克菲尔德在其报告中宣称，12名参试儿童直到接种过MMR疫苗后身体正常，但在此之前，报告谎称5名参试儿童存在发育问题。迪尔还发现，当他将韦克菲尔德报告数据与儿童病历及儿童父母所述进行对比之后，发现所有病例都与真实情况大相径庭，病例数据都被篡改过。

据报道，韦克菲尔德最近还出了一本书，专门论述“疫苗与自闭症密切相关”。但是骗局被揭露之后，记者一直没能打通他的电话，也未见他本人对此有任何评论。目前此人居住在美国。去年5月，英国取消了韦克菲尔德的行医资格，这位英国MMR疫苗致残案主角也因其不道德行为被英国医学委员会开除。

记者迪尔的调查报告发表于伦敦《星期日泰晤士报》、英国第四频道电视台和1月6日《英国医学杂志》在线版。同期《英国医学杂志》刊登编辑菲奥娜·戈德里及其同事的评论文章，称韦克菲尔德的如此不靠谱的研究其实是“一场精心策划的骗局”，此人在其它期刊上发表的论文都必须重新严格审查。另外，多项研究也证实MMR疫苗与自闭症毫无关联。

Study Linking Vaccine to Autism Was Fraud, Journal Reports


LONDON (AP) — The first study to link a childhood vaccine to autism was based on doctored information about the children involved, according to a new report on the widely discredited research.

The conclusions of the 1998 paper by Andrew Wakefield and colleagues was renounced by 10 of its 13 authors and later retracted by the medical journal Lancet, where it was published. Still, the suggestion the MMR shot was connected to autism spooked parents worldwide and immunization rates for measles, mumps and rubella have never fully recovered.

A new examination found, by comparing the reported diagnoses in the paper to hospital records, that Wakefield and colleagues altered facts about patients in their study.

The analysis, by British journalist Brian Deer, found that despite the claim in Wakefield's paper that the 12 children studied were normal until they had the MMR shot, five had previously documented developmental problems. Deer also found that all the cases were somehow misrepresented when he compared data from medical records and the children's parents.

Wakefield could not be reached for comment despite repeated calls and requests to the publisher of his recent book, which claims there is a connection between vaccines and autism that has been ignored by the medical establishment. Wakefield now lives in the U.S. where he enjoys a vocal following including celebrity supporters like Jenny McCarthy.

Deer's article was paid for by the Sunday Times of London and Britain's Channel 4 television network. It was published online Thursday in the medical journal, BMJ.

In an accompanying editorial, BMJ editor Fiona Godlee and colleagues called Wakefield's study "an elaborate fraud." They said Wakefield's work in other journals should be examined to see if it should be retracted.

Last May, Wakefield was stripped of his right to practice medicine in Britain. Many other published studies have shown no connection between the MMR vaccination and autism.

But measles has surged since Wakefield's paper was published and there are sporadic outbreaks in Europe and the U.S. In 2008, measles was deemed endemic in England and Wales.