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[细菌] 2016新书《Bacterial Therapy of Cancer: Methods and Protocols》

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发表于 2016-6-27 05:28:42 | 只看该作者 回帖奖励 |倒序浏览 |阅读模式
Bacterial Therapy of Cancer:Methods and Protocols

Editors: Hoffman, Robert M (Ed.)

Includes cutting-edge methods and protocols

Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts


About this book
This volume explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chapters in this book cover a broad range of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for precise quantification of the interactions between tumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging of bacteria-mediated cancer therapy using bio-luminescent bacteria, methods to achieve remote-control of therapeutic gene expression in tumor-targeting bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to drug sensitivity by S. typhimurium A1-R. This book concludes with a chapter on the future potential of bacterial therapy of cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Thorough and informative, Bacterial Therapy of Cancer: Methods and Protocols is a valuable resource for anyone who is interested in cancer and bacterial therapy.

本书更多介绍:http://www.springer.com/us/book/9781493935130

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 楼主| 发表于 2016-6-27 05:30:53 | 只看该作者
早在150年前,活细菌就已经被用来治疗癌症。1868年,德国医生Busch首先报道了部分肿瘤患者在感染肺炎链球菌后,体内的肿瘤生长被抑制甚至被彻底清除。在之后的三十年内,美国医生Coley和另外一名德国医生Fehleisen又分别报道了细菌感染可以抑制肿瘤这一现象。
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