[转移贴]抗病毒药物药效测定方法（二）

viruskiller

原贴由pumcpzg 发表于 2009-10-18 14:56

抗病毒药物药效测定方法（二）



Herpesviruses Assays Protocols



Herpes Screening Process



General Approach for Determining Antiviral Activity and Toxicity for Herpesviruses



A.  Screening Assays for Activity Against HSV-1, HSV-2, CMV, and VZV



B.   Confirmation of Antiviral Activity and Toxicity for HSV, CMV, and VZV



C.   Assay Systems for Determining Antiviral Activity Against EBV and Toxicity to Lymphoblastic Cells



D.  Assay systems for Determining Antiviral Activity Against  HHV-6, HHV-8 and Toxicity to Lymphoblastic Cells.



E.   Laboratory Procedures for Determining Antiviral Efficacy and Toxicity for Herpesviruses



1.     Preparation of compounds for in vitro testing



2.     Screening and confirmation assays for HSV, VZV, and CMV



3.     Screening and Confirmation Assays for EBV



4.     Assays Against HHV-6A, HHV-6B, and HHV-8.



5.     Screening and Confirmation Assays for Toxicity



6.     Reporting of results.



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Herpesviruses Assays Protocols.pdf (156.28 KB) 下载次数: 67

2009-10-18 14:56

viruskiller

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