2017年是中国病毒学发展史上重要一年,这一年以国内科研机构和学者为主要完成者在国际重要病毒学期刊发表了多项标志性成果,继去年年度盘点后,中国病毒学论坛微信号将继续对一年来国内学者取得成果进行盘点。2017年国内学者在Journal of Virology(JVI)共发文108篇,较2016年增加7篇;从单位发文来看,中科院上海巴斯德所以11篇雄踞首位,其他超过2篇的单位依次为中国医学科学院病原生物学研究所8篇,中科院武汉病毒所8篇,中国农科院哈尔滨兽医研究所8篇,华中农业大学7篇,武汉大学5篇,吉林大学、中科院微生物所、中国农业大学、南京农业大学、中山大学、苏州大学各4篇,清华大学、中国疾病预防控制中心、军事医学科学院、复旦大学、南开大学各3篇,西北农林科技大学、浙江大学、泰山医学院、北京大学、河南农业大学各2篇。 (IF=4.606)是由美国微生物协会(American Society for Microbiology,ASM)在1967年创办的老牌病毒学期刊,半月刊。该杂志在病毒学领域33份杂志中排名第5位,文章发表量排名第1。目前主编为加里弗尼亚大学Rozanne M. Sandri-Goldin教授。在1998至2013的15年期间,其IF一直保持在5.0以上;但自从2014年开始,其IF降到5.0以下。其原因可能有如下两种:该杂志在2011至2012年接受发表基因组通告(genome announcement,此文章类型于2013年单独成立为期刊)类型的文章,此类型文章的引用数相对较低;另外,2010年该协会创办了另一旗帜性开放获取期刊mBio,导致不少“原本”投Journal of Virology的高质量论文的流失。此杂志主要偏重于发表病毒学领域基础机制性的研究工作,包括病毒结构及组装、病毒基因组复制及基因表达调控、病毒基因多样性及进化、病毒与细胞之间相互作用、病毒感染的细胞反应、病毒致病机理及免疫和疫苗及抗病毒药物研发等方面。其文章类型主要包括Original Articles、 Minireviews、 Commentaries和Letters to the Editor。该杂志审稿速度比较快,一般在3个星期左右;但其接受率偏低,大约为30%。Journal of Virology按文章接受后排版的页面来收费,ASM协会会员费用为75美金/页,非会员为150美金/页。 1. Guo Y, Liu B, Ding Z, Li G, Liu M, Zhu D, Sun Y, Dong S, Lou Z. 2017. Distinct mechanism for the formation of the ribonucleoprotein complex of tomato spotted wilt virus. J Virol 91:e00892-17. (清华大学 娄智勇,南开大学 Dong shishang ) 2. Kuang W, Zhang H, Wang M, Zhou N-Y, Deng F, Wang H, Gong P, Hu Z. 2017. Three conserved regions in baculovirus sulfhydryl oxidase P33 are critical for enzymatic activity and function. J Virol 91:e01158-17.(中科院武汉病毒所 胡志红,龚鹏) 3. Yang L, Zhu W, Li X, Chen M, Wu J, Yu P, Qi S, Huang Y, Shi W, Dong J, Zhao X, Huang W, Li Z, Zeng X, Bo H, Chen T, Chen W, Liu J, Zhang Y, Liang Z, Shi W, Shu Y, Wang D. 2017. Genesis and spread of newly emerged highly pathogenic H7N9 avian viruses in mainland China. J Virol 91:e01277-17.(中国疾控中心 舒跃龙、王大燕) 4. Li Z, Zhao K, Lan Y, Lv X, Hu S, Guan J, Lu H, Zhang J, Shi J, Yang Y, Song D, Gao F, He W. 2017. Porcine hemagglutinating encephalomyelitis virus enters Neuro-2a cells via clathrin-mediated endocytosis in a Rab5-, cholesterol-, and pH-dependent manner. J Virol 91:e01083-17.(吉林大学,贺文琦 ) 5. Qin Y, Xue B, Liu C, Wang X, Tian R, Xie Q, Guo M, Li G, Yang D, Zhu H. 2017. NLRX1 mediates MAVS degradation to attenuate the hepatitis C virus-induced innate immune response through PCBP2. J Virol 91:e01264-17.*(湖南大学,朱海珍,杨大荣) 6. Tao W, Gan T, Guo M, Xu Y, Zhong J. 2017. Novel stable Ebola virus minigenome replicon reveals remarkable stability of the viral genome. J Virol 91:e01316-17(中科院上海巴斯德所,钟劲) 7. Huang H, Li S, Zhang Y, Han X, Jia B, Liu H, Liu D, Tan S, Wang Q, Bi Y, Liu WJ, Hou B, Gao GF, Zhang F. 2017. CD8+ T cell immune response in immunocompetent mice during Zika virus infection. J Virol 91:e00900-17.(中科院微生物所,张福萍、高福) 8. Liu Z-Y, Yu J-Y, Huang X-Y, Fan H, Li X-F, Deng Y-Q, Ji X, Cheng M-L, Ye Q, Zhao H, Han J-F, An X-P, Jiang T, Zhang B, Tong Y-G, Qin C-F. 2017. Characterization of cis-acting RNA elements of Zika virus by using a self-splicing ribozyme-dependent infectious clone. J Virol 91:e00484-17.(军事医学科学院 秦成峰) 9. Zheng F, Lu G, Li L, Gong P, Pan Z. 2017. Uncoupling of protease trans-cleavage and helicase activities in pestivirus NS3. J Virol 91:e01094-17.(武汉大学,潘兹书) 10. Zhang R, Xu A, Qin C, Zhang Q, Chen S, Lang Y, Wang M, Li C, Feng W, Zhang R, Jiang Z, Tang J. 2017. Pseudorabies virus dUTPase UL50 induces lysosomal degradation of type I interferon receptor 1 and antagonizes the alpha interferon response. J Virol 91:e01148-17.(中国农业大学,唐军) 11. Xia L, Dai L, Yu Q, Yang Q. 2017. Persistent transmissible gastroenteritis virus infection enhances enterotoxigenic Escherichia coli K88 adhesion by promoting epithelial-mesenchymal transition in intestinal epithelial cells. J Virol 91:e01256-17.(南京农业大学,杨倩) 12. Wang S, Liu Y, Guo J, Wang P, Zhang L, Xiao G, Wang W. 2017. Screening of FDA-approved drugs for inhibitors of Japanese encephalitis virus infection. J Virol 91:e01055-17.(中科院武汉病毒所,Wang wei) 13. Wang Z, Yang H, Chen Y, Tao S, Liu L, Kong H, Ma S, Meng F, Suzuki Y, Qiao C, Chen H. 2017. A single-amino-acid substitution at position 225 in hemagglutinin alters the transmissibility of Eurasian avian-like H1N1 swine influenza virus in guinea pigs. J Virol 91:e00800-17.(中国农科院哈尔滨兽医研究所,陈化兰) 14. Guo Y, Yue Q, Gao J, Wang Z, Chen Y-R, Blissard GW, Liu T-X, Li Z. 2017. Roles of cellular NSF protein in entry and nuclear egress of budded virions of Autographa californica multiple nucleopolyhedrovirus. J Virol 91:e01111-17.(西北农林科技大学,刘同先、李朝飞) 15. Liu C-C, Zhang Y-N, Li Z-Y, Hou J-X, Zhou J, Kan L, Zhou B, Chen P-Y. 2017. Rab5 and Rab11 are required for clathrin-dependent endocytosis of Japanese encephalitis virus in BHK-21 cells. J Virol 91:e01113-17.(南京农业大学,周斌) 16. Ke W, Fang L, Jing H, Tao R, Wang T, Li Y, Long S, Wang D, Xiao S. 2017. Cholesterol 25-hydroxylase inhibits porcine reproductive and respiratory syndrome virus replication through enzyme activity-dependent and -independent mechanisms. J Virol 91:e00827-17.(华中农业大学,肖少波、方六荣) 17. Xiao X, Lei X, Zhang Z, Ma Y, Qi J, Wu C, Xiao Y, Li L, He B, Wang J. 2017. Enterovirus 3A facilitates viral replication by promoting phosphatidylinositol 4-kinase IIIβ–ACBD3 interaction. J Virol 91:e00791-17.(中国医学科学院病原生物学研究所 王建伟) 18. Wang C, Wang C, Li Q, Wang Z, Xie W. 2017. Crystal structure and thermostability characterization of enterovirus D68 3Dpol. J Virol 91:e00876-17.(中山大学 谢伟、王忠) 19. Zhu T, Song H, Peng R, Shi Y, Qi J, Gao GF. 2017. Crystal structure of the Marburg virus nucleoprotein core domain chaperoned by a VP35 peptide reveals a conserved drug target for filovirus. J Virol 91:e00996-17.(中科院微生物所,高福、齐建勋) 20. Yin P, Li Y, Zhang L. 2017. Sec24C-dependent transport of claudin-1 regulates hepatitis C virus entry. J Virol 91:e00629-17.(中国医学科学院病原生物学研究所,张磊亮) 21. Chen X, Zhang Q, Bai J, Zhao Y, Wang X, Wang H, Jiang P. 2017. The nucleocapsid protein and nonstructural protein 10 of highly pathogenic porcine reproductive and respiratory syndrome virus enhance CD83 production via NF-κB and Sp1 signaling pathways. J Virol 91:e00986-17.(南京农业大学,姜平) 22. Lei X, Zhang Z, Xiao X, Qi J, He B, Wang J. 2017. Enterovirus 71 inhibits pyroptosis through cleavage of gasdermin D. J Virol 91:e01069-17.(中国医学科学院病原生物学研究所 王建伟) 23. Zhang H-L, Ye H-Q, Liu S-Q, Deng C-L, Li X-D, Shi P-Y, Zhang B. 2017. West Nile virus NS1 antagonizes interferon beta production by targeting RIG-I and MDA5. J Virol 91:e02396-16.(中科院武汉病毒所,张波) 24. Ding X, Zhang X, Chong H, Zhu Y, Wei H, Wu X, He J, Wang X, He Y. 2017. Enfuvirtide (T20)-based lipopeptide is a potent HIV-1 cell fusion inhibitor: implications for viral entry and inhibition. J Virol 91:e00831-17.(中国医学科学院病原生物学研究所 何玉先,清华大学 王新泉) 25. Shi Y, Kawana-Tachikawa A, Gao F, Qi J, Liu C, Gao J, Cheng H, Ueno T, Iwamoto A, Gao GF. 2017. Conserved Vδ1 binding geometry in a setting of locus-disparate pHLA recognition by δ/αβ T cell receptors (TCRs): insight into recognition of HIV peptides by TCRs. J Virol 91:e00725-17.(中科院微生物所 高福) 26. Lin X, Sun R, Zhang F, Gao Y, Bin L, Lan K. 2017. The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus inhibits expression of SUMO/sentrin-specific peptidase 6 to facilitate establishment of latency. J Virol 91:e00806-17.(武汉大学 蓝柯) 27. Wang W, Lin X-D, Liao Y, Guan X-Q, Guo W-P, Xing J-G, Holmes EC, Zhang Y-Z. 2017. Discovery of a highly divergent coronavirus in the Asian house shrew from China illuminates the origin of the alphacoronaviruses. J Virol 91:e00764-17.(中国疾控中心 张永振) 28. Tu C, Zeng Z, Qi P, Li X, Yu Z, Guo C, Xiong F, Xiang B, Zhou M, Gong Z, Liao Q, Yu J, He Y, Zhang W, Li X, Li Y, Li G, Xiong W. 2017. Genome-wide analysis of 18 Epstein-Barr viruses isolated from primary nasopharyngeal carcinoma biopsy specimens. J Virol 91:e00301-17.(中南大学 熊炜, 李桂源) 29. Liu B, Dong S, Li G, Wang W, Liu X, Wang Y, Yang C, Rao Z, Guo Y. 2017. Structural insight into nucleoprotein conformation change chaperoned by VP35 peptide in Marburg virus. J Virol 91:e00825-17.(南开大学 饶子和,郭宇) 30. Zhong X, Wang ZQ, Xiao R, Cao L, Wang Y, Xie Y, Zhou X. 2017. Mimic phosphorylation of a βC1 protein encoded by TYLCCNB impairs its functions as a viral suppressor of RNA silencing and a symptom determinant. J Virol 91:e00300-17.(浙江大学 周雪平,谢艳) 31. Liu N, Zhang J, Yang X, Jiao T, Zhao X, Li W, Zhu J, Yang P, Jin J, Peng J, Li Z, Ye X. 2017. HDM2 promotes NEDDylation of hepatitis B virus HBx to enhance its stability and function. J Virol 91:e00340-17.(中科院微生物所 叶昕,302医院 李志伟) 32. Han C, Zeng X, Yao S, Gao L, Zhang L, Qi X, Duan Y, Yang B, Gao Y, Liu C, Zhang Y, Wang Y, Wang X. 2017. Voltage-dependent anion channel 1 interacts with ribonucleoprotein complexes to enhance infectious bursal disease virus polymerase activity. J Virol 91:e00584-17.(中国农科院哈兽研 王笑梅,王永强) 33. Zou Z, Meng Z, Ma C, Liang D, Sun R, Lan K. 2017. Guanylate-binding protein 1 inhibits nuclear delivery of Kaposi's sarcoma-associated herpesvirus virions by disrupting formation of actin filament. J Virol 91:e00632-17.(武汉大学 蓝柯) 34. Qian S, Fan W, Liu T, Wu M, Zhang H, Cui X, Zhou Y, Hu J, Wei S, Chen H, Li X, Qian P. 2017. Seneca Valley virus suppresses host type I interferon production by targeting adaptor proteins MAVS, TRIF, and TANK for cleavage. J Virol 91:e00823-17.(华中农业大学 钱平,李祥敏) 35. Zhong L, Shu W, Dai W, Gao B, Xiong S. 2017. Reactive oxygen species-mediated c-Jun NH2-terminal kinase activation contributes to hepatitis B virus X protein-induced autophagy via regulation of the beclin-1/Bcl-2 interaction. J Virol 91:e00001-17.(苏州大学 熊思东,复旦大学 高波) 36. Guo C, Zhu Z, Guo Y, Wang X, Yu P, Xiao S, Chen Y, Cao Y, Liu X. 2017. Heparanase upregulation contributes to porcine reproductive and respiratory syndrome virus release. J Virol 91:e00625-17. (中山大学 刘小红) 37. Li Z, Li Y, Bi Y, Zhang H, Yao Y, Li Q, Cun W, Dong S. 2017. Extracellular interactions between hepatitis C virus and secreted apolipoprotein E. J Virol 91:e02227-16.(中国医学科学院医学生物学研究所 董少忠,Cun wei) 38. Zhao M, Zheng Z-Z, Chen M, Modjarrad K, Zhang W, Zhan L-T, Cao J-L, Sun Y-P, McLellan JS, Graham BS, Xia N-S. 2017. Discovery of a prefusion respiratory syncytial virus F-specific monoclonal antibody that provides greater in vivo protection than the murine precursor of palivizumab. J Virol 91:e00176-17.(厦门大学 夏宁邵) 39. Wu Y, Wang J, Fan S, Chen R, Liu Y, Zhang J, Yuan H, Liang R, Zhang N, Xia C. 2017. Structural definition of duck major histocompatibility complex class I molecules that might explain efficient cytotoxic T lymphocyte immunity to influenza A virus. J Virol 91:e02511-16.(中国农业大学 夏春, 张念之) 40. Lu L-F, Li S, Wang Z-X, Du S-Q, Chen D-D, Nie P, Zhang Y-A. 2017. Grass carp reovirus VP41 targets fish MITA to abrogate the interferon response. J Virol 91:e00390-17.(中科院水生生物所 张永安) 41. Xu J, Xiang Y. 2017. Membrane penetration by bacterial viruses. J Virol 91:e00162-17. (清华大学 向烨) 42. Rui Y, Su J, Wang H, Chang J, Wang S, Zheng W, Cai Y, Wei W, Gordy JT, Markham R, Kong W, Zhang W, Yu X-F. 2017. Disruption of MDA5-mediated innate immune responses by the 3C proteins of coxsackievirus A16, coxsackievirus A6, and enterovirus D68. J Virol 91:e00546-17.(吉林大学 于晓方、张文艳) 43. Zhang Z, Dong Z, Li J, Carr MJ, Zhuang D, Wang J, Zhang Y, Ding S, Tong Y, Li D, Shi W. 2017. Protective efficacies of formaldehyde-inactivated whole-virus vaccine and antivirals in a murine model of coxsackievirus A10 infection. J Virol 91:e00333-17.(泰山医学院 史卫峰,李东) 44. Du Y, Chen M, Yang J, Jia Y, Han S, Holmes EC, Cui J. 2017. Molecular evolution and emergence of H5N6 avian influenza virus in central China. J Virol 91:e00143-17. (中科院武汉病毒所 崔杰) 45. He B, Huang X, Zhang F, Tan W, Matthijnssens J, Qin S, Xu L, Zhao Z, Yang L, Wang Q, Hu T, Bao X, Wu J, Tu C. 2017. Group A rotaviruses in Chinese bats: genetic composition, serology, and evidence for bat-to-human transmission and reassortment. J Virol 91:e02493-16.(军事医学科学院军事兽医研究所 涂长春,广西兽医研究所 吴健敏) 46. Jiang H-F, Wang W, Jiang X, Zeng W-B, Shen Z-Z, Song Y-G, Yang H, Liu X-J, Dong X, Zhou J, Sun J-Y, Yu F-L, Guo L, Cheng T, Rayner S, Zhao F, Zhu H, Luo M-H. 2017. ORF7 of varicella-zoster virus is required for viral cytoplasmic envelopment in differentiated neuronal cells. J Virol 91:e00127-17(中科院武汉病毒所,罗敏华) 47. Mao Q, Liao Z, Li J, Liu Y, Wu W, Chen H, Chen Q, Jia D, Wei T. 2017. Filamentous structures induced by a phytoreovirus mediate viral release from salivary glands in its insect vector. J Virol 91:e00265-17. (福建农林大学 魏太云) 48. Xin Q-L, Deng C-L, Chen X, Wang J, Wang S-B, Wang W, Deng F, Zhang B, Xiao G, Zhang L-K. 2017. Quantitative proteomic analysis of mosquito C6/36 cells reveals host proteins involved in Zika virus infection. J Virol 91:e00554-17. (中科院武汉病毒所 肖庚富,张磊砢) 49. Xu C, Sun X, Taylor A, Jiao C, Xu Y, Cai X, Wang X, Ge C, Pan G, Wang Q, Fei Z, Wang Q. 2017. Diversity, distribution, and evolution of tomato viruses in China uncovered by small RNA sequencing. J Virol 91:e00173-17.(上海师范大学 王全华) 50. Li L-F, Yu J, Zhang Y, Yang Q, Li Y, Zhang L, Wang J, Li S, Luo Y, Sun Y, Qiu H-J. 2017. Interferon-inducible oligoadenylate synthetase-like protein acts as an antiviral effector against classical swine fever virus via the MDA5-mediated type I interferon-signaling pathway. J Virol 91:e01514-16.(中国农科院哈尔滨兽医研究所 仇华吉,Sun yuan) 51. Chong H, Xue J, Xiong S, Cong Z, Ding X, Zhu Y, Liu Z, Chen T, Feng Y, He L, Guo Y, Wei Q, Zhou Y, Qin C, He Y. 2017. A lipopeptide HIV-1/2 fusion inhibitor with highly potent in vitro, ex vivo, and in vivo antiviral activity. J Virol 91:e00288-17.(中国医学科学院病原生物学研究所 何玉先,秦川) 52. Wang S, Ren H, Jiang W, Chen H, Hu H, Chen Z, Zhou P. 2017. Divergent requirement of Fc-Fcγ receptor interactions for in vivo protection against influenza viruses by two pan-H5 hemagglutinin antibodies. J Virol 91:e02065-16.(中科院上海巴斯德所 周保罗) 53. Zhu X, Wang D, Zhou J, Pan T, Chen J, Yang Y, Lv M, Ye X, Peng G, Fang L, Xiao S. 2017. Porcine deltacoronavirus nsp5 antagonizes type I interferon signaling by cleaving STAT2. J Virol 91:e00003-17.(华中农业大学 肖少波、方六荣) 54. Zhang X, Zhou T, Yang J, Lin Y, Shi J, Zhang X, Frabutt DA, Zeng X, Li S, Venta PJ, Zheng Y-H. 2017. Identification of SERINC5-001 as the predominant spliced isoform for HIV-1 restriction. J Virol 91:e00137-17.(中国农科院哈尔滨兽医研究所 郑永辉) 55. Luo X, Guo L, Zhang J, Xu Y, Gu W, Feng L, Wang Y. 2017. Tight junction protein occludin is a porcine epidemic diarrhea virus entry factor. J Virol 91:e00202-17.(中国农科院哈尔滨兽医研究所 Wang yue) 56. Liu K, Qian Y, Jung Y-S, Zhou B, Cao R, Shen T, Shao D, Wei J, Ma Z, Chen P, Zhu H, Qiu Y. 2017. mosGCTL-7, a C-type lectin protein, mediates Japanese encephalitis virus infection in mosquitoes. J Virol 91:e01348-16.(南京农业大学 陈溥言,第二军医大学 zhu huaimin) 57. Yang X, Li H, Sun H, Fan H, Hu Y, Liu M, Li X, Tang H. 2017. Hepatitis B virus-encoded microRNA controls viral replication. J Virol 91:e01919-16(天津医科大学 汤华) 58. Zhang L, Li H, Hai Y, Yin W, Li W, Zheng B, Du X, Li N, Zhang Z, Deng Y, Zeng R, Wei L. 2017. CpG in combination with an inhibitor of Notch signaling suppresses formalin-inactivated respiratory syncytial virus-enhanced airway hyperresponsiveness and inflammation by inhibiting Th17 memory responses and promoting tissue-resident memory cells in lungs. J Virol 91:e02111-16.(河北医科大学 zeng ruihong,wei lin) 59. Huang J, Zhu L, Qiu C, Xu X, Zhang L, Ding X, Liao Q, Xu J, Zhang X. 2017. MicroRNA miR-126-5p enhances the inflammatory responses of monocytes to lipopolysaccharide stimulation by suppressing cylindromatosis in chronic HIV-1 infection. J Virol 91:e02048-16.(复旦大学 徐建青,张晓燕) 60. Zheng X, Wang X, Tu F, Wang Q, Fan Z, Gao G. 2017. TRIM25 is required for the antiviral activity of zinc finger antiviral protein. J Virol 91:e00088-17.(中科院生物物理研究所 高光侠) 61. Wang H, Guo H, Su J, Rui Y, Zheng W, Gao W, Zhang W, Li Z, Liu G, Markham RB, Wei W, Yu X-F. 2017. Inhibition of Vpx-mediated SAMHD1 and Vpr-mediated host helicase transcription factor degradation by selective disruption of viral CRL4 (DCAF1) E3 ubiquitin ligase assembly. J Virol 91:e00225-17(天津大学/吉林大学 于晓方,吉林大学 Wei Wei) 62. Liu H, Zhang L, Sun J, Chen W, Li S, Wang Q, Yu H, Xia Z, Jin X, Wang C. 2017. Endoplasmic reticulum protein SCAP inhibits dengue virus NS2B3 protease by suppressing its K27-linked polyubiquitylation. J Virol 91:e02234-16.(中科院上海生化细胞所 wang chen,中科院上海巴斯德所 金侠) 63. Ma H, Han P, Ye W, Chen H, Zheng X, Cheng L, Zhang L, Yu L, Wu X, Xu Z, Lei Y, Zhang F. 2017. The long noncoding RNA NEAT1 exerts antihantaviral effects by acting as positive feedback for RIG-I signaling. J Virol 91:e02250-16.(第四军医大学 张芳琳,雷迎峰) 64. Jiang W, Wang S, Chen H, Ren H, Huang X, Wang G, Chen Z, Chen L, Chen Z, Zhou P. 2017. A bivalent heterologous DNA virus-like-particle prime-boost vaccine elicits broad protection against both group 1 and 2 influenza A viruses. J Virol 91:e02052-16.(中科院上海巴斯德所 周保罗) 65. Zhang Z, Dong Z, Wei Q, Carr MJ, Li J, Ding S, Tong Y, Li D, Shi W. 2017. A neonatal murine model of coxsackievirus A6 infection for evaluation of antiviral and vaccine efficacy. J Virol 91:e02450-16.(泰山医学院 史卫峰,李东) 66. Ye J, Chen Z, Li Y, Zhao Z, He W, Zohaib A, Song Y, Deng C, Zhang B, Chen H, Cao S. 2017. Japanese encephalitis virus NS5 inhibits type I interferon (IFN) production by blocking the nuclear translocation of IFN regulatory factor 3 and NF-κB. J Virol 91:e00039-17.(华中农业大学 曹胜波) 67. Chen J, Xu W, Chen Y, Xie X, Zhang Y, Ma C, Yang Q, Han Y, Zhu C, Xiong Y, Wu K, Liu F, Liu Y, Wu J. 2017. Matrix metalloproteinase 9 facilitates hepatitis B virus replication through binding with type I interferon (IFN) receptor 1 to repress IFN/JAK/STAT signaling. J Virol 91:e01824-16.(武汉大学 吴建国,刘映乐 ) 68. Hu Y, Li W, Gao T, Cui Y, Jin Y, Li P, Ma Q, Liu X, Cao C. 2017. The severe acute respiratory syndrome coronavirus nucleocapsid inhibits type I interferon production by interfering with TRIM25-mediated RIG-I ubiquitination. J Virol 91:e02143-16.(中国医学科学院病原生物学研究所 Xuan Liu and Cheng Cao) 69. Chen S, Hou C, Bi H, Wang Y, Xu J, Li M, James AA, Huang Y, Tan A. 2017. Transgenic clustered regularly interspaced short palindromic repeat/Cas9-mediated viral gene targeting for antiviral therapy of Bombyx mori nucleopolyhedrovirus. J Virol 91:e02465-16.(中科院植生所 谭安江,黄勇平) 70. Fan C, Ye X, Ku Z, Kong L, Liu Q, Xu C, Cong Y, Huang Z. 2017. Beta-propiolactone inactivation of coxsackievirus A16 induces structural alteration and surface modification of viral capsids. J Virol 91:e00038-17.(中科院上海巴斯德所 黄忠,上海科学中心 丛尧) 71. Pu J, Sun H, Qu Y, Wang C, Gao W, Zhu J, Sun Y, Bi Y, Huang Y, Chang K-C, Cui J, Liu J. 2017. M gene reassortment in H9N2 influenza virus promotes early infection and replication: contribution to rising virus prevalence in chickens in China. J Virol 91:e02055-16.(中国农业大学 刘金华,中科院武汉病毒所 崔杰) 72. Ren Q, Huang X, Cui Y, Sun J, Wang W, Zhang X. 2017. Two white spot syndrome virus microRNAs target the Dorsal gene to promote virus infection in Marsupenaeus japonicus shrimp. J Virol 91:e02261-16.(浙江大学 章晓波) 73. Tong Y, Chi X, Yang W, Zhong J. 2017. Functional analysis of hepatitis C virus (HCV) envelope protein E1 using a trans-complementation system reveals a dual role of a putative fusion peptide of E1 in both HCV entry and morphogenesis. J Virol 91:e02468-16.(中科院上海巴斯德所 钟劲) 74. Zheng W, Ling L, Li Z, Wang H, Rui Y, Gao W, Wang S, Su X, Wei W, Yu X-F. 2017. Conserved interaction of lentiviral Vif molecules with HIV-1 Gag and differential effects of species-specific Vif on virus production. J Virol 91:e00064-17(吉林大学 于晓方 Wei Wei) 75. Li Y, Zhou M, Luo Z, Zhang Y, Cui M, Chen H, Fu ZF, Zhao L. 2017. Overexpression of interleukin-7 extends the humoral immune response induced by rabies vaccination. J Virol 91:e02324-16.(华中农业大学 赵凌) 76. Tang X, Yang Y, Xia X, Zhang C, Yang X, Song Y, Dai X, Wang M, Zhou D. 2017. Recombinant adenoviruses displaying matrix 2 ectodomain epitopes on their fiber proteins as universal influenza vaccines. J Virol 91:e02462-16.(中科院上海巴斯德所 周东明) 77. Zhao D, Liang L, Wang S, Nakao T, Li Y, Liu L, Guan Y, Fukuyama S, Bu Z, Kawaoka Y, Chen H. 2017. Glycosylation of the hemagglutinin protein of H5N1 influenza virus increases its virulence in mice by exacerbating the host immune response. J Virol 91:e02215-16.(中国农科院哈尔滨兽医研究所 陈化兰) 78. Yan Y, He Y, Boson B, Wang X, Cosset F-L, Zhong J. 2017. A point mutation in the N-terminal amphipathic helix α0 in NS3 promotes hepatitis C virus assembly by altering core localization to the endoplasmic reticulum and facilitating virus budding. J Virol 91:e02399-16.(中科院上海巴斯德所 钟劲) 79. Su C, Zheng C. 2017. Herpes simplex virus 1 abrogates the cGAS/STING-mediated cytosolic DNA-sensing pathway via its virion host shutoff protein, UL41. J Virol 91:e02414-16.(苏州大学 郑春福) 80. Huang Z, Pan M, Zhu S, Zhang H, Wu W, Yuan M, Yang K. 2017. The Autographa californica multiple nucleopolyhedrovirus ac83 gene contains a cis-acting element that is essential for nucleocapsid assembly. J Virol 91:e02110-16(中山大学 杨凯) 81. Yang L, Zhu W, Li X, Bo H, Zhang Y, Zou S, Gao R, Dong J, Zhao X, Chen W, Dong L, Zou X, Xing Y, Wang D, Shu Y. 2017. Genesis and dissemination of highly pathogenic H5N6 avian influenza viruses. J Virol 91:e02199-16. (中国疾控中心 舒跃龙,王大燕) 82. Qi P, Liu K, Wei J, Li Y, Li B, Shao D, Wu Z, Shi Y, Tong G, Qiu Y, Ma Z. 2017. Nonstructural protein 4 of porcine reproductive and respiratory syndrome virus modulates cell surface swine leukocyte antigen class I expression by downregulating β2-microglobulin transcription. J Virol 91:e01755-16(中国农科院上海兽医研究所 马志永,邱亚峰) 83. Ye R, Su C, Xu H, Zheng C. 2017. Herpes simplex virus 1 ubiquitin-specific protease UL36 abrogates NF-κB activation in DNA sensing signal pathway. J Virol 91:e02417-16(苏州大学 郑春福) 84. Dai A, Cao S, Dhungel P, Luan Y, Liu Y, Xie Z, Yang Z. 2017. Ribosome profiling reveals translational upregulation of cellular oxidative phosphorylation mRNAs during vaccinia virus-induced host shutoff. J Virol 91:e01858-16.(中山大学 谢志) 85. Wang Y, Duan Y, Han C, Yao S, Qi X, Gao Y, Maier HJ, Britton P, Chen L, Zhang L, Gao L, Gao H, Shen N, Wang J, Wang X. 2017. Infectious bursal disease virus subverts autophagic vacuoles to promote viral maturation and release. J Virol 91:e01883-16.(中国农科院哈尔滨兽医研究所 王笑梅) 86. Li C, Wang Z, Cao Y, Wang L, Ji J, Chen Z, Deng T, Jiang T, Cheng G, Qin FX-F. 2017. Screening for novel small-molecule inhibitors targeting the assembly of influenza virus polymerase complex by a bimolecular luminescence complementation-based reporter system. J Virol 91:e02282-16(中国医学科学院苏州系统医学研究所 程根宏,秦晓峰) 87. Xu J-D, Jiang H-S, Wei T-D, Zhang K-Y, Wang X-W, Zhao X-F, Wang J-X. 2017. Interaction of the small GTPase Cdc42 with arginine kinase restricts white spot syndrome virus in shrimp. J Virol 91:e01916-16.(山东大学 wang jinxing) 88. Zhang P, Su C, Jiang Z, Zheng C. 2017. Herpes simplex virus 1 UL41 protein suppresses the IRE1/XBP1 signal pathway of the unfolded protein response via its RNase activity. J Virol 91:e02056-16.(苏州大学 郑春福) 89. Ma H, Jiang L, Qiao S, Zhi Y, Chen X-X, Yang Y, Huang X, Huang M, Li R, Zhang G-P. 2017. The crystal structure of the fifth scavenger receptor cysteine-rich domain of porcine CD163 reveals an important residue involved in porcine reproductive and respiratory syndrome virus infection. J Virol 91:e01897-16(河南农业大学 河南省农科院 张改平,李睿) 90. Hao S, Zhang J, Chen Z, Xu H, Wang H, Guan W. 2017. Alternative polyadenylation of human bocavirus at its 3′ end is regulated by multiple elements and affects capsid expression. J Virol 91:e02026-16.(中科院武汉病毒所 关武祥) 91. Zhang S, Jiang Y, Cheng Q, Zhong Y, Qin Y, Chen M. 2017. Inclusion body fusion of human parainfluenza virus type 3 regulated by acetylated α-tubulin enhances viral replication. J Virol 91:e01802-16.(武汉大学 陈明周) 92. Ye C, Han X, Yu Z, Zhang E, Wang L, Liu H. 2017. Infectious bursal disease virus activates c-Src to promote α4β1 integrin-dependent viral entry by modulating the downstream Akt-RhoA GTPase-actin rearrangement cascade. J Virol 91:e01891-16.(浙江农林大学 刘合宾 ) 93. Jing H, Fang L, Ding Z, Wang D, Hao W, Gao L, Ke W, Chen H, Xiao S. 2017. Porcine reproductive and respiratory syndrome virus nsp1α inhibits NF-κB activation by targeting the linear ubiquitin chain assembly complex. J Virol 91:e01911-16.(华中农业大学 肖少波) 94. Ye C, Wang W, Cheng L, Li G, Wen M, Wang Q, Zhang Q, Li D, Zhou P, Su L. 2017. Glycosylphosphatidylinositol-anchored anti-HIV scFv efficiently protects CD4 T cells from HIV-1 infection and deletion in hu-PBL mice. J Virol 91:e01389-16.(中科院上海巴斯德所 周保罗) 95. Wang Z, Li M, Zhou M, Zhang Y, Yang J, Cao Y, Wang K, Cui M, Chen H, Fu ZF, Zhao L. 2017. A novel rabies vaccine expressing CXCL13 enhances humoral immunity by recruiting both T follicular helper and germinal center B cells. J Virol 91:e01956-16.(华中农业大学 赵凌) 96. Chen J, Shi X, Zhang X, Wang A, Wang L, Yang Y, Deng R, Zhang G-P. 2017. MicroRNA 373 facilitates the replication of porcine reproductive and respiratory syndrome virus by its negative regulation of type I interferon induction. J Virol 91:e01311-16.(河南农业大学 张改平,河南师范大学Xibao Shi) 97. Zhao F, Zhao T, Deng L, Lv D, Zhang X, Pan X, Xu J, Long G. 2017. Visualizing the essential role of complete virion assembly machinery in efficient hepatitis C virus cell-to-cell transmission by a viral infection-activated split-intein-mediated reporter system. J Virol 91:e01720-16.(中科院上海巴斯德所 龙钢) 98. Wang J, Qiao L, Hou Z, Luo G. 2017. TIM-1 promotes hepatitis C virus cell attachment and infection. J Virol 91:e01583-16.(北京大学 罗光湘) 99. Li J, Yao Y, Chen Y, Xu X, Lin Y, Yang Z, Qiao W, Tan J. 2017. Enterovirus 71 3C promotes apoptosis through cleavage of PinX1, a telomere binding protein. J Virol 91:e02016-16.(南开大学 谈娟,乔文涛) 100. Zhang M, Li X, Deng Z, Chen Z, Liu Y, Gao Y, Wu W, Chen Z. 2017. Structural biology of the arterivirus nsp11 endoribonucleases. J Virol 91:e01309-16(中国农业大学 陈忠周) 101. Wang J, Li J, Zhao L, Cao M, Deng T. 2017. Dual roles of the hemagglutinin segment-specific noncoding nucleotides in the extended duplex region of the influenza A virus RNA promoter. J Virol 91:e01931-16.(中国医科科学院病原生物学研究所 邓涛) 102. Zhu P, Liang L, Shao X, Luo W, Jiang S, Zhao Q, Sun N, Zhao Y, Li J, Wang J, Zhou Y, Zhang J, Wang G, Jiang L, Chen H, Li C. 2017. Host cellular protein TRAPPC6AΔ interacts with influenza A virus M2 protein and regulates viral propagation by modulating M2 trafficking. J Virol 91:e01757-16.(中国农科院哈尔滨兽医研究所 李呈军) 103. Li C, Wang H-B, Kuang W-D, Ren X-X, Song S-T, Zhu H-Z, Li Q, Xu L-R, Guo H-J, Wu L, Wang J-H. 2017. Naf1 regulates HIV-1 latency by suppressing viral promoter-driven gene expression in primary CD4+ T cells. J Virol 91:e01830-16.(中科院上海巴斯德所 王建华) 104. Zhang A, Zhao L, Li N, Duan H, Liu H, Pu F, Zhang G, Zhou E-M, Xiao S. 2017. Carbon monoxide inhibits porcine reproductive and respiratory syndrome virus replication by the cyclic GMP/protein kinase G and NF-κB signaling pathway. J Virol 91:e01866-16.(西北农林科技大学 肖书奇,周恩民) 105. Su S, Zhu Y, Ye S, Qi Q, Xia S, Ma Z, Yu F, Wang Q, Zhang R, Jiang S, Lu L. 2017. Creating an artificial tail anchor as a novel strategy to enhance the potency of peptide-based HIV fusion inhibitors. J Virol 91:e01445-16.(复旦大学 姜世勃,陆路) 106. Tai W, Wang Y, Fett CA, Zhao G, Li F, Perlman S, Jiang S, Zhou Y, Du L. 2017. Recombinant receptor-binding domains of multiple Middle East respiratory syndrome coronaviruses (MERS-CoVs) induce cross-neutralizing antibodies against divergent human and camel MERS-CoVs and antibody escape mutants. J Virol 91:e01651-16.(军事医学科学院 周育森) 107. Xiong S, Borrego P, Ding X, Zhu Y, Martins A, Chong H, Taveira N, He Y. 2017. A helical short-peptide fusion inhibitor with highly potent activity against human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus. J Virol 91:e01839-16.(中国医学科学院病原生物学研究所 何玉先) 108. Fan H, Qiao L, Kang K-D, Fan J, Wei W, Luo G. 2017. Attachment and postattachment receptors important for hepatitis C virus infection and cell-to-cell transmission. J Virol 91:e00280-17.(北京大学 罗光湘)
|