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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) 3 E0 t% r' M! B1 O3 H( s7 F& q
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
' b- O6 e# {9 ^' i N: N% k【出 版 社】: Humana Press; 2011 edition
( P7 e/ n* L1 v2 z" F# G% o【出版日期】: (November 30, 2011) ) z" q4 x, i; r) Z5 P
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
7 }) p. x! G+ V+ H【目 录】:
# `3 ?: N8 [3 f( r8 K. rHardcover: 475 pages
: y/ _, I( D; Y# H8 a( }8 s' G) r Language: English/ Y7 I& ^2 E# W& H! [9 `, A
ISBN-10: 1617793698: l0 J* b7 V! J
ISBN-13: 978-16177936911 c5 a P* K1 ^+ g, @$ ]0 k% H
下载地址:
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或者:http://3721up.com/4eyi# @" g$ N4 e: H: ^/ q' G1 Q7 Y
或:http://good.gd/1754392.htm
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