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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
; N5 x c( x- K2 U# ]/ w8 f【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor), e4 X6 V, _, p8 \; W: r- K7 O
【出 版 社】: Humana Press; 2011 edition; x6 j. w$ Q4 |# F0 N8 J- F% Q! k
【出版日期】: (November 30, 2011)
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
7 B9 _6 P. o0 s, H' X j【目 录】: 5 q1 w4 M9 j$ T. W: I& m; E
Hardcover: 475 pages0 I/ ?/ u, t8 ]$ [$ S3 }
Language: English
9 y, ~. u- @" H9 UISBN-10: 16177936982 f2 c) ~2 o( G6 p
ISBN-13: 978-1617793691
8 H% B0 Z; g& J, |2 a下载地址:/ t0 z$ R# A0 x5 m8 x" O9 M5 j: v1 B+ f
http://dl.dbank.com/c0afbmkn85# g2 ?" ]6 c/ b/ P6 {
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- ~5 {- g C) F m1 u0 f3 Q9 J: B或:http://good.gd/1754392.htm
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