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Vaccine Analysis: Strategies, Principles, and Control (英语) 精装 – 2014年12月9日 : {; t# t) ]0 G6 i
Brian K. Nunnally (编者), Vincent E. Turula (编者), Robert D. Sitrin (编者)
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1 |! G# d# U0 o/ l h0 DThis book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities.( k: f" U$ R2 Y' F3 j
Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.% J/ _7 ]1 Z8 K3 P4 I( @) x
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