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本帖最后由 douban 于 2016-8-27 12:00 编辑 2 z8 ]+ n# \0 P N
7 B+ A0 K9 r, u: g& oDevelopment of Novel Vaccines% s+ Z/ R3 h4 B* I( V1 N* N
6 L6 [4 B* R3 @3 z1 ?Skills, Knowledge and Translational Technologies0 V4 ^, y: N' [8 `* [
2 k4 V# ?9 D* O$ [# H" w( K2 U% bEditors: von Gabain, Alexander, Klade, Christoph (Eds.) 1 H5 @; {) p6 q6 M
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About this book6 P, n9 r5 C$ B
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“Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions. Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.
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Table of contents (11 chapters)
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3 F0 e" o% f1 i& VSkills, Knowledge, and Translational Technologies Leading to Novel Vaccines1 D. u9 }$ Y6 K9 N: Y) Y! _* p
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Alkan, Şefik Ş.
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Pages 1-26
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Finding Protective Bacterial Antigens3 u9 y Q# R8 ? u9 w- n! @
$ a6 Q9 ^, P% I. ]Grandi, Guido (et al.)* p9 k& V6 R$ A7 _# [
7 V# D ~2 h X% [* l3 h1 XPages 27-44
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Enhancing and Tailoring the Immunogenicity of Vaccines with Novel Adjuvants, m5 v* f, ], c2 X! C t
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Fox, Christopher B. (et al.)/ q1 d. I+ p3 R
0 {( _0 J7 T2 D6 N: H7 _Pages 45-72& Z& ~+ K' Y& L B. Q1 i
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' w! g3 T! k. S$ VVaccine Delivery: Beyond Needles
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Flyer, David C. (et al.)# o, h/ G/ S3 ~
# ]; T8 e! T3 Z6 ?7 ^5 v$ qPages 73-86
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" n% t1 c* H) G( F1 F' cEmploying Live Microbes for Vaccine Delivery
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Loessner, Holger (et al.)
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Pages 87-124
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. z ?0 I2 {0 jSynthesizing Vaccines with Microbes
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Wacker, Michael (et al.)$ P! y5 T4 g- M3 y. N3 C
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Pages 125-1445 y j A: l7 s
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( k, B5 Y+ s r2 f6 ?0 F+ F; EPurification and Formulation: Silent but Important Players in Vaccine Development+ f( u$ l5 k5 y5 ]3 h* ^) n
1 ]4 |' |/ m% C' ^Schlegl, Robert (et al.)5 E s' E/ C' b% M5 H: e/ K9 M
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Pages 145-188
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# P! L. U. p" I, v; Q* wCutting-Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines
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Arnon, Ruth (et al.)7 ~" t$ P: `9 ?# V3 s$ s% }
. P$ i { {* b8 H- ~1 EPages 189-204' @1 x* B% c; `: [$ I: n
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! m5 i9 m( W$ f: I3 S. {Cutting Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines' _0 x# Y6 o+ ], }5 N$ s2 l! O
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Roose, Kenny (et al.)8 O8 e. z+ }* S
) i: E& L5 L& C l; Y+ IPages 205-232# B/ t( f) F% U' v
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$ V* ]* T3 R, \' R, |Examples of Novel Registered Prophylactic Vaccines, HPV, and JEV. [7 K6 T# z, y' _* R$ K/ Z9 u
8 {% h2 A$ O- F) @3 i" e FDubischar-Kastner, Katrin (et al.)
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8 A2 v( G$ U& d LPages 233-2862 b5 r; Z. D6 O% B+ K
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! l8 ]8 ?: p* MThe Bumpy Road Toward Vaccine Registration: How to Overcome Regulatory Hurdles7 s6 e( Q0 y/ x5 Q4 I* T
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Pfleiderer, Michael
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Pages 287-3000 P% Q/ w8 @2 E7 q" t; }
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