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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
1 z% l. ^4 f0 o! R; j/ |【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
* W! g. p3 ]$ A( b {$ Y- T7 [: E+ C【出 版 社】: Humana Press; 2011 edition, |$ |4 U; h$ R* D W5 D) ~, d
【出版日期】: (November 30, 2011) 7 J: e; r g2 N2 S' P6 ~) z0 d
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.5 U! h: z* z% J% r1 t$ _/ f+ J
【目 录】: 4 A/ g! q- N. [/ K m. q# H
Hardcover: 475 pages
! S) W( ^6 Y0 L0 J6 Y Language: English7 G0 l' j& J9 ? s8 Q2 l% Q9 s3 C
ISBN-10: 1617793698
: t8 E0 K+ R/ k! O, WISBN-13: 978-1617793691' {7 K9 O# S0 X( h7 z
下载地址:
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