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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
3 m& M# W8 F( X8 F【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
# j: k5 f9 Z; o" y* o8 h6 p/ }【出 版 社】: Humana Press; 2011 edition+ f. ]& _. W+ ?) V
【出版日期】: (November 30, 2011)
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5 ?! |4 ^. {6 r1 J# A, }【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.- n# [4 A! o4 z; B" B" I
【目 录】:
2 {4 G4 }- n9 S. |2 j5 _8 JHardcover: 475 pages
" S% q/ Y& C- K Language: English
) L% V: e9 Y: lISBN-10: 1617793698
. s# c' d$ W6 NISBN-13: 978-16177936918 b! i: a6 u D; d: f( R" k
下载地址:: x5 f" k' G" d- J4 N' {
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