2011版：Adeno-Associated Virus: Methods and Protocols

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【书名版次】：             Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)     
8 G* R: H7 d: i2 B8 W3 M* V/ Q【作    者】：Richard O. Snyder (Editor), Philippe Moullier (Editor)
: l3 l, o4 }9 i) e( ~【出 版 社】:     Humana Press; 2011 edition
【出版日期】： (November 30, 2011)         

0 U, T6 X/ q2 N8 S【简    介】： Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of  gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
4 ?' t5 @$ J- x! R【目    录】：  
Hardcover: 475 pages
Language: English
ISBN-10: 1617793698
ISBN-13: 978-1617793691
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