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; M$ r! H H3 j* H9 ?! j. PViral Pathogenesis and Immunity 2nd 名著再版2 Y4 ^: L. c( o9 D1 b
【书名版次】：Viral Pathogenesis and Immunity Second（Second edition）
8 s/ n* I$ A a/ D0 `' U6 u【作 者】：Neal Nathanson1 {6 \3 c8 G7 s/ v
【出 版 社】: Academic Press. u1 b* `& B/ z
【简 介】：: v* [( |+ Y) e$ W
名著再版 - g; M1 y9 ^$ w, C8 y! _" [* e
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This book is the direct offspring of Viral Pathogenesis,
* Q1 }% }: H' ^( k/ E7 C; Fpublished in 1997. Having read several drafts of all the
- i+ c B3 ^- A4 A% j. zchapters in Viral Pathogenesis, it was clear that the large3 Z- D2 X+ G1 I/ I
book contained a wealth of information, but that it was5 C, b9 _& X7 v3 w" j
unsuited for readers who desired an introduction to the. D6 `9 w* u X% U4 c
topic. From that observation sprang the plan for a short
" i) T' B1 ]1 A7 Qversion that could be used as an introductory text or for! g3 z5 u' T+ p0 D) \ T" d
self-education.1 {1 b* \2 H2 y) Q& d& G9 n
An introductory text clearly benefits from the3 Z7 U7 [* L1 u( G2 p# }+ E% b6 H" h
coherence provided by a single author, but suffers from+ j1 `+ n: l5 ?' w9 B L# H
the finite expertise of any single researcher. Therefore, a: L. {6 A7 {# p1 y
compromise was devised, in which each chapter was coauthored
/ e% d/ T1 r; k' E: yby an expert in the specific area under consideration.& c6 U. c/ }* m9 E: a
This strategy was facilitated by the successful7 \& e2 A* Y. i0 T; A+ K
collaborations that had been developed during the
: z! p+ R2 G! Z/ p! M/ T' x4 epreparation of Viral Pathogenesis. The text includes: Q/ r1 c, u" m( a2 C
references published through to June, 2006.- x9 {& k& q R p, W1 N7 i3 i
I would like to acknowledge the contributions of the
+ z D- W! J8 @: h+ |# a) D4 ico-authors. Their advice and expertise has been essential
8 i2 C) I, S! H- O4 {to the planning and execution of this undertaking and it) p: Y" p* @7 ^8 i
has been a continual pleasure to work with them. They
& ^1 R- h, ]+ m* v9 G6 R' m( j. |$ }have provided extremely cogent suggestions that have Z: l/ T$ l) A$ F
given the book an enhanced level of authority that could
9 F( \" C; I8 L {not otherwise have been achieved.! V, g1 J! @& J8 ~+ K/ M3 u
Lisa Tickner and the staff at Academic Press,6 L6 W8 @1 O; D7 x
London, have been an ongoing source of support both
4 @" R. {8 j4 J8 u# u' ubecause of their enthusiasm for this book and their- ~+ U* ]' j: o; W3 k
highly professional expertise in all phases of the project.% L% `; @# p1 S, V$ J
Wendy Jackelow provided the outstanding illustrations6 g7 c1 {! ~" K5 I5 z s/ g
rendered from a wide variety of often primitive sketches.
; S# V3 ~$ f; y' T4 oNeal Nathanson
+ _/ S; q* M- G& h0 {8 f, {Philadelphia
" S4 b8 O! c& e. [" r2 W4 h, t【出版日期】：2007
i% [9 Z9 j1 }) E! c3 Z& `/ y【Contents】:$ J4 y7 k7 ]; j* Z: R6 |7 J
/ B4 v! A9 V p$ y! }3 @7 eList of Co-authors vii
. [0 D" b# F/ Q) d$ u X# _2 sPreface ix- R$ E. S- ?- G- e7 y3 w$ N+ E# J
Introduction xi
g1 @2 d; I3 ~. n, C; m& aPart I Essentials of Viral Pathogenesis 1
# o; `+ x* B0 a1 Historical Roots 31 }$ C) i2 \/ P( o
Neal Nathanson and Frederick A.Murphy2 T& P- e- X5 k& T
2 The Sequential Steps in Viral Infection 14% B+ `) k% ~* v9 p6 Y0 h! p, W
Neal Nathanson and Frederick A.Murphy
- ^& @* o# i$ f# P3 Cellular Receptors and Viral Tropism 273 ?$ A' |0 O" \' J5 m/ G
Neal Nathanson and Kathryn V. Holmes
4 Y- f1 h, J& v4 i4 Virus–Cell Interactions 414 K, W5 Z% d8 l! E$ j' F
Neal Nathanson and Diane E. Griffin
7 s! b1 W5 W( ]# w/ ?1 @* @Part II Host Responses to Viral Infection 57
8 E# t, r1 m) B0 |9 Z0 i+ W6 c3 Y5 Innate Immunity 59
4 I* Y2 n( ^" X( h9 e6 U6 c' c/ INeal Nathanson and Christine A. Biron# _" s; f+ s, ?+ F
6 Immune Responses to Viral Infection 72 Q. q' l" v8 o
Neal Nathanson and Rafi Ahmed
' H6 {- A# v+ ], R9 l7 Virus-Induced Immunopathology 88
# T" T; U' }' x; |" l4 nNeal Nathanson and Rafi Ahmed, c# z. e s( P" J; R- O; D
8 Virus-Induced Immunosuppression 99- m- j! r8 v! D, W" Z& F, d
Neal Nathanson and Diane E. Griffin1 u# m3 `5 a [' [
Part III Virus–Host Interactions 1117 _9 [5 q9 n4 k: }
9 Viral Virulence 113
% [' Q' ^* |0 w& k8 mNeal Nathanson and Francisco
/ N/ r9 B; m6 U* {# H* n8 ^# oGonzalez-Scarano
3 Q4 l( W2 w2 m: _# _10 Viral Persistence 130
7 w0 P" J# R0 W8 }4 sNeal Nathanson and Francisco
" E: \9 }/ F& J" U' d3 s, B% CGonzalez-Scarano: g8 o$ Y+ d( J1 E1 B/ P
11 Viral Oncogenesis: Retroviruses 146
9 d* b5 w) ~/ T9 X) d5 s, Y1 SNeal Nathanson and Harriet L. Robinson/ ^) N2 p* y. M/ j0 P4 g; s5 C
12 Viral Oncogenesis: DNA Viruses 158
, ~5 T* O0 l8 I8 \( `) \! t: ENeal Nathanson and Erle S. Robertson }. C& c; o+ ~. J& X9 W2 P
13 Host Susceptibility to Viral Diseases 174
; o5 E5 U, z: p3 v5 w1 _/ X; B0 A1 YNeal Nathanson and Margo A. Brinton! a; Q9 _2 U# C3 N4 K7 t5 U2 O8 y% I
14 HIV, SIV and the Pathogenesis of AIDS 1850 t9 r: Y, H4 `$ M$ K4 {( I- l
Neal Nathanson and Julie Overbaugh
, O3 N3 o4 r! b, JPart IV Ecology and Control of Viral 201
1 t* ^7 Y ~1 k* r2 w! F9 }Infections
/ B+ d$ k# a P3 b9 T" X2 x15 Emerging Viral Diseases 203) T$ }1 @/ G. ~
Neal Nathanson and Frederick A.Murphy
, d+ X2 w# p( \2 S$ V( {16 Antiviral Therapy 2216 x7 {/ c# e5 g6 u7 ~3 [% q
Neal Nathanson and Douglas D. Richman5 O" V0 W. g& x9 I" T! a
17 Viral Vaccines 234
6 C/ F/ s% `5 M1 dNeal Nathanson and Harriet L. Robinson
% W( k. ?" Y+ E) Q& y$ m2 `$ g6 O/ OGlossary and Abbreviations 253" t. H4 S# i7 H+ _
Index 259
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