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2 A. Q! n) |0 d; W7 H* `Viral Pathogenesis and Immunity 2nd 名著再版- m9 C. y- n! t' A$ ?
【书名版次】：Viral Pathogenesis and Immunity Second（Second edition）
+ D! d8 o; G3 t1 E+ |【作 者】：Neal Nathanson
, V! p1 V/ W, z3 ^【出 版 社】: Academic Press' d0 t# o8 r% C* F7 Q
【简 介】：
6 Y6 S/ e; @% X6 ]8 J! I 名著再版
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( {# {$ Z' @. s3 f4 w& n2 ?0 j This book is the direct offspring of Viral Pathogenesis,
# R# c8 F1 ^' {3 W; _0 Tpublished in 1997. Having read several drafts of all the
! `2 J& `& m) y7 ?) ?3 \chapters in Viral Pathogenesis, it was clear that the large; m$ q' |2 X/ Y' A, _. s, W5 f' B
book contained a wealth of information, but that it was
2 l$ s/ X5 x6 L5 n9 n8 sunsuited for readers who desired an introduction to the+ x6 }1 ~$ G6 G9 a$ T0 S# @6 g& W" Q
topic. From that observation sprang the plan for a short
: y9 K9 l( Z1 c" |% I( Y: y0 uversion that could be used as an introductory text or for+ ^% O" Y6 I' G- Y* k {* @( k% ^
self-education.0 `$ q. b/ d; ^# G/ a$ d3 s, X6 k
An introductory text clearly benefits from the
5 h6 X& R: ~: t- `, @coherence provided by a single author, but suffers from
' n" K+ {' ?. c8 p+ Nthe finite expertise of any single researcher. Therefore, a
# N3 y+ q. e( L: O$ f* \+ y( i" ocompromise was devised, in which each chapter was coauthored
" T: X1 n: q4 ]; N2 g# pby an expert in the specific area under consideration.2 t3 _. p2 E- z9 q/ Y `3 i9 f
This strategy was facilitated by the successful: u4 P; B- c, c0 e( u( ^
collaborations that had been developed during the
3 V: \2 `" p. f `- fpreparation of Viral Pathogenesis. The text includes- w( E, b9 ` y2 W: M, O5 c
references published through to June, 2006.
3 W3 J- i {/ j3 G8 |3 DI would like to acknowledge the contributions of the
) ?' C' B2 `9 w4 p u- F* jco-authors. Their advice and expertise has been essential
1 n4 [1 A1 Q& d4 e" _# j$ uto the planning and execution of this undertaking and it) W z. }( ?3 w3 O. [) i* w) s
has been a continual pleasure to work with them. They2 k' o; L9 k1 b
have provided extremely cogent suggestions that have8 |$ s5 T9 l* Z5 d9 e0 S
given the book an enhanced level of authority that could
% h1 R% b X7 G! V2 c: i1 |9 vnot otherwise have been achieved.3 K! H8 ~# w$ ^: Z3 c# l
Lisa Tickner and the staff at Academic Press,, d5 V; x, Q3 k! c* Y- E
London, have been an ongoing source of support both0 L( G/ E7 Y% B' F0 z5 o
because of their enthusiasm for this book and their
0 ^3 l' F+ Q# v: H8 D4 i# |/ Ihighly professional expertise in all phases of the project.( [6 h: ?2 t) I. g; n& Q; K
Wendy Jackelow provided the outstanding illustrations
2 u/ z7 I/ G# w1 }1 }. ^: V: C8 Prendered from a wide variety of often primitive sketches.' @. r5 y0 _7 ^1 K9 ~
Neal Nathanson% S+ j& p2 \9 I6 u$ l
Philadelphia
$ _8 R# @# m) Y2 r0 S i$ {9 I【出版日期】：2007
1 E( W1 y! F1 X8 E) X" x【Contents】:
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9 k; [9 h3 V; t9 |) |' Z7 mList of Co-authors vii* Y0 Y/ S3 E m. _& u0 k+ u8 W
Preface ix& |( k# k6 k6 y" v( Z1 A) f- e* N; u
Introduction xi8 z( {( X- B; ?
Part I Essentials of Viral Pathogenesis 13 k. h1 Y) o w; \4 y$ N% _' ~1 n" c
1 Historical Roots 3$ Y4 d2 k- O6 n' y$ o, ~0 j/ |
Neal Nathanson and Frederick A.Murphy& Z. c# |- z: n" S- C
2 The Sequential Steps in Viral Infection 14( m) G. M$ F6 A
Neal Nathanson and Frederick A.Murphy9 E5 p" Y7 I; v4 `7 m, a0 a( C
3 Cellular Receptors and Viral Tropism 27
' G( p6 g" {% ^. N8 cNeal Nathanson and Kathryn V. Holmes: V( n0 ~" |; w2 p* V8 K1 s* z
4 Virus–Cell Interactions 41' i' A6 R% @3 |, H
Neal Nathanson and Diane E. Griffin
% {; j& U2 v [- \Part II Host Responses to Viral Infection 57& X! c' m8 {5 ?6 d* s; V
5 Innate Immunity 59- v9 \4 C) Y0 u4 u# t6 D# c u
Neal Nathanson and Christine A. Biron
- w1 W, h7 ]# H9 q6 Immune Responses to Viral Infection 72
# a$ l# j8 b! x7 s+ qNeal Nathanson and Rafi Ahmed( M/ S4 M- x& g
7 Virus-Induced Immunopathology 88 \/ I# o3 m7 j ?
Neal Nathanson and Rafi Ahmed w, m2 `; H" i- p' X
8 Virus-Induced Immunosuppression 99
/ i9 c" W: G* ?4 |9 @Neal Nathanson and Diane E. Griffin0 v4 V$ t0 U! X `: i4 e* j8 K
Part III Virus–Host Interactions 111
/ ^3 U0 K: m. N7 K' _% J& v9 Viral Virulence 113
. T& p6 y) N" a# ]( J8 [5 A- V! RNeal Nathanson and Francisco
+ G, q+ |# `: T) q7 h/ R% u; o0 C7 ]Gonzalez-Scarano, O! L# G6 S5 d b7 `1 J, z
10 Viral Persistence 130) T. |) e: A" W+ C
Neal Nathanson and Francisco
4 h# b8 W0 M; i/ z& ?4 xGonzalez-Scarano4 C& \7 ?' R5 x$ j
11 Viral Oncogenesis: Retroviruses 146
5 Y; D* l4 g- x/ b* R4 E0 \Neal Nathanson and Harriet L. Robinson
7 d! L- O8 x# T3 _" B12 Viral Oncogenesis: DNA Viruses 158& D T3 V& T" X
Neal Nathanson and Erle S. Robertson
" P$ X/ n! {9 X; n* y0 d, N13 Host Susceptibility to Viral Diseases 174
4 p2 h# a# p S. A8 U1 YNeal Nathanson and Margo A. Brinton
. ~. N- H: Z1 E' G' N8 m8 L& _14 HIV, SIV and the Pathogenesis of AIDS 185
1 s, j) ~8 V; E; vNeal Nathanson and Julie Overbaugh/ f- _1 {# y' {
Part IV Ecology and Control of Viral 201& n; x) f5 l; D
Infections
7 L0 g1 a0 @8 A' W( [" i% g15 Emerging Viral Diseases 203
8 B* G2 Y/ F! i7 k I' X: ENeal Nathanson and Frederick A.Murphy$ w& L' L9 L: \
16 Antiviral Therapy 221
8 ~ }: d% V) iNeal Nathanson and Douglas D. Richman
/ u* {. |5 ?) A17 Viral Vaccines 234
/ i( Q/ } N5 z3 i( ]Neal Nathanson and Harriet L. Robinson$ J" \, M3 x. @/ W
Glossary and Abbreviations 253
* D2 h+ q8 b& GIndex 259
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