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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
A2 Y8 r: d. ^ m, o【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)0 g/ e9 v) \8 \- a; w( `8 s; M
【出 版 社】: Humana Press; 2011 edition
, a; R: B) @4 D7 s; p8 n$ \2 I7 d【出版日期】: (November 30, 2011) # k" `) A' g$ g6 R$ W5 u
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.4 Z8 u" }, q- F9 q
【目 录】:
9 G6 p& \4 F7 {3 wHardcover: 475 pages
" H& Z2 V" H. H# h5 k) I8 N Language: English
- Q2 g& ?8 m4 @/ N* ]ISBN-10: 16177936985 P" z5 ^# m3 o2 \0 K- K7 L
ISBN-13: 978-1617793691
' k+ T# ~( G" I- T下载地址:
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+ I( ?/ ~$ R0 w! [6 J$ R) j或:http://good.gd/1754392.htm
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