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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) " @6 Z" O- b& p# k5 u
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
4 S: c% X/ G% c) m【出 版 社】: Humana Press; 2011 edition
1 P5 u* ?5 ^/ A& z, [! X5 E) p【出版日期】: (November 30, 2011) 2 R3 f* _' B5 N+ q( o
: a0 g5 F8 n/ p1 i3 n" Y( i【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.9 h8 H! J! f& E! u. ], R6 [' T" b
【目 录】:
: K) N2 K0 G! E) Z# q& VHardcover: 475 pages
, T0 F6 C+ i( a6 G- h* U6 C# D) l Language: English
( M7 \) I9 B7 A2 w6 CISBN-10: 1617793698: f! v* Q: M _+ ~. x0 {
ISBN-13: 978-1617793691
$ n. s! m9 H) U5 _下载地址:
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