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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) 8 D, T- D( ?2 c$ J9 u& G
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)+ R$ F4 z; [8 g. w+ b
【出 版 社】: Humana Press; 2011 edition
4 L3 q q5 c2 W( ~7 v3 f【出版日期】: (November 30, 2011) 4 X) [; N5 a- v5 A/ C5 \
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.! C8 m K E( N$ o* V
【目 录】: ! c7 Z/ s! m1 A
Hardcover: 475 pages
5 K/ i7 m, x, _4 G4 j Language: English
" l. ]5 A+ F9 \$ M0 M% R7 G, @, bISBN-10: 1617793698& h B* Q$ d4 N/ _
ISBN-13: 978-1617793691$ c) e" ?, X: A6 G7 {# d) p
下载地址:
4 v" f9 d( p# B# S/ r http://dl.dbank.com/c0afbmkn85
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( s2 c$ e5 H9 V& Y5 ?" w$ t或:http://good.gd/1754392.htm
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