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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) 8 N. P4 y$ \: o6 A) Y' n3 I/ r
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)8 E0 Y) e {- o
【出 版 社】: Humana Press; 2011 edition7 \6 L6 z* j9 o! A- {
【出版日期】: (November 30, 2011) 5 W: g6 k4 e& {) f" ?
# z* W8 A) O; n( U【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
! D# g3 w% @5 E! c1 V+ w# U- r5 [. o【目 录】:
6 g2 x4 b) X/ e XHardcover: 475 pages& a# Q1 f |, R2 \7 X' @" ~- ^$ C
Language: English
% B4 w9 b/ h: M! RISBN-10: 1617793698
Y4 t V v R$ M- BISBN-13: 978-1617793691
) w7 V, R$ H) U- j' s& Y% e下载地址:" T) N( G6 Y% M1 j3 o/ B2 q
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