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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
6 P+ f4 Q0 V/ T! f/ Q【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)' o4 L# j) w6 V v# |1 G" r/ G0 @
【出 版 社】: Humana Press; 2011 edition
* Z" t; }, L( ~" d Z【出版日期】: (November 30, 2011) . Y8 K/ q3 \: J' j9 s5 \* j
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
8 }, D$ N" X8 t2 `【目 录】: 9 O+ i! m1 Y3 |# @. c- h
Hardcover: 475 pages5 [. X g0 ]- ?9 s5 Q
Language: English& z0 A: j( q8 `- V% n8 `0 p" l
ISBN-10: 1617793698 g K$ ?) h* k j
ISBN-13: 978-1617793691
- E$ i* {8 W! s; Q; e+ C0 U5 W下载地址:
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或:http://good.gd/1754392.htm' `7 S! ~( v' X7 m
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