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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
$ j/ Y5 n. Y* D t" |【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)' \/ L7 @! H/ v3 M: r
【出 版 社】: Humana Press; 2011 edition5 X$ A4 |, F9 A( F2 V
【出版日期】: (November 30, 2011)
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$ V! U+ y2 \) t【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
. C* Q3 U2 R2 u# f2 m% r0 w8 K9 W【目 录】:
: b I7 l& w6 [& i i$ KHardcover: 475 pages' S% R! |; d% C) o+ j% J% a8 U
Language: English
. F0 E M2 K' j8 mISBN-10: 1617793698( ~7 B) d. y2 ~/ r' \
ISBN-13: 978-1617793691 s$ M) W" I- y; u% }! u( H% j& I
下载地址:
' x3 j4 r% A# T. B+ N# s http://dl.dbank.com/c0afbmkn85
/ g0 ?) x; M' t% h6 g$ N或者:http://3721up.com/4eyi* M9 B! Z0 r3 ]' ]
或:http://good.gd/1754392.htm: p M$ [7 Y) ^) p( e
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