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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
! |3 s8 c `5 A【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
2 G: X( Z; a# g, e) I6 P【出 版 社】: Humana Press; 2011 edition, S; B! s% j1 {; V! H' P9 L
【出版日期】: (November 30, 2011)
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
9 S( \) O8 d0 j$ s0 a) B. I【目 录】:
8 U3 o3 H# Z d( BHardcover: 475 pages
; |8 _5 |: U& P Language: English. O& M! X) D2 Z& W. Z
ISBN-10: 1617793698
. ?3 z) d2 `6 E2 sISBN-13: 978-1617793691
: Y( V' B/ z6 T5 L下载地址:
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或:http://good.gd/1754392.htm
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