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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) U3 z/ ~" P1 C7 |7 h$ l0 }
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor), O6 p8 I x3 X& f7 x
【出 版 社】: Humana Press; 2011 edition
, C5 H' w5 Q2 ^9 V3 C3 j# I【出版日期】: (November 30, 2011) , t7 g0 ~5 R- ?4 T. }
# q: p* W2 ]! M- @【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
+ J/ {9 K: `, n【目 录】:
* ~: w' H1 |. z" `: `# ~! SHardcover: 475 pages
# S/ _4 J$ Z: R0 x, d M Language: English) }5 g0 Y7 ]7 }% s" U( I/ e; r
ISBN-10: 1617793698
$ y- w" S0 \+ b: z4 M: }! Z# EISBN-13: 978-1617793691
+ n! l A5 q; o4 Q" g" o下载地址:
# Y( i0 Z. O- N1 N/ j2 W2 Z: ^ http://dl.dbank.com/c0afbmkn854 U$ E; G, _) l. J# Q
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# _8 \7 Q* H$ }! c0 H或:http://good.gd/1754392.htm( K3 \0 |+ R1 I4 e* V
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