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原贴由davay发表于 2009-11-29 01:525 x' J3 W& T' y( z; t
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本帖最后由 davay 于 2009-11-29 01:54 编辑! b' E# d* j. l ~% d
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http://jvi.asm.org/cgi/reprint/JVI.00151-09v1
) l8 V9 k* g, W, b, H这篇文章是病毒学专业最顶级杂志Journal of Virology的主编写的一篇review.里面回顾拉,病毒学的发展,和展望.我觉得有用的是,说到下一代病毒学家,或者说病毒学工作者需要具备的素质.
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7 {" w+ q/ n9 t5 yTRAINING VIROLOGISTS FOR THE FUTURE/ j r( A' E k9 l% g9 P( C
. \# o, T; E4 {$ R7 x& KHow can virologists take advantage of all of these new opportunities for scholarship
: J( \. r1 ~6 x2 y8 Land application? To address this question, we must consider what constitutes optimum% o1 l# K+ s% N# a- Z% j
training for virologists in the 21st century. Tomorrow’s advances will require a combination
: T B1 G+ P" k7 O1 `% k/ e! lof small, tightly focused groups and large, multidisciplinary teams. Traditional teams of basic3 u4 Z+ e& N1 t$ `( w. T
scientists working with clinicians will be augmented by mathematicians, physicists, and
# Y5 D1 q/ Q) ~7 kpopulation biologists, among others. Integrating new technology advances with classical
$ Y8 x( b& z" w: Y. N; {epidemiology and clinical approaches will not be a simple pedagogical exercise. Training the; \9 o1 g F) I, A
next generation of scientists who can undertake this research will require more diverse course
1 K9 Q' w6 ]" e t4 Rofferings, enhanced training opportunities, especially involving interdisciplinary
- E( @+ p# \* [. y" ycollaboration and computational approaches, and instruction in teamwork. To facilitate
. r4 V; w ~4 ~3 q- y/ Iprofessional advancement, we will need to develop new strategies to recognize and reward+ [* |$ B2 C4 y$ r
individual contributions to group scientific efforts as team science becomes more and more
* }. }! M+ V1 Z4 ? zprevalent.
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Systems biology approaches, large-scale genetic screens, metagenomics of host and5 I7 B, K- p8 K, h8 A
viral genes from related viruses present a unique challenge for training. These approaches
- t% x. }0 v$ B0 mwill produce enormous amounts of information that will challenge our capacity to integrate it" y; D* W# g! V1 h1 B1 r) N8 V9 P0 E
into useful conceptual frameworks. Imaging technology will reveal the dynamics of5 k9 j% w4 R* p" Z# ?
biological interactions at every level, yet produce huge sets of data that strain current systems% I, W n: i* I4 h0 h
for information storage and retrieval. Methods to search, screen, recover, and use this
9 n# C7 ^. I1 |9 L( Z& {information will provide new avenues for discovery and require a new generation of6 O8 P% |9 K) l% c N
virologists with special expertise in computational methods and information technology. |
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